What are the responsibilities and job description for the MES functional Lead position at Smart IT Frame LLC?
MES Functional & Technical Lead
Contract
St. Louis MO (Onsite)
Key Responsibilities
- Lead MES implementation and support activities by providing strong functional and technical expertise across MES applications, system interfaces, user access management, infrastructure components, shopfloor devices, and operational support processes.
- Partner with Manufacturing, Operations, Quality, MSAT, Validation, and IT teams to understand business requirements, identify process gaps, and translate site-specific needs into scalable MES solutions.
- Drive business process reengineering, process harmonization, and continuous improvement initiatives to align manufacturing operations with MES best practices.
- Collaborate with vendors, implementation partners, offshore development teams, and support organizations to deliver MES enhancements, integrations, and issue resolutions.
- Support MES deployment lifecycle activities including requirements gathering, design review, testing, validation, implementation, go-live, hypercare, and steady-state operations.
- Coordinate user acceptance testing (UAT), system validation activities, and documentation to ensure compliance with regulatory and quality standards.
- Provide on-site and remote support to manufacturing users, troubleshoot production issues, perform root cause analysis, and implement corrective and preventive actions.
- Manage and support MES integrations with enterprise systems such as ERP, LIMS, Quality Management Systems, and other manufacturing applications.
- Ensure system reliability, data integrity, security compliance, and adherence to change management and support procedures.
- Facilitate cross-functional stakeholder meetings, requirements workshops, and status reviews to ensure successful project execution and business alignment.
- Monitor system performance, identify optimization opportunities, and drive continuous improvements in MES processes and user experience.
- Support training, knowledge transfer, and adoption activities to ensure successful utilization of MES solutions across manufacturing sites.
Preferred Qualifications
- Experience working in regulated manufacturing environments such as Pharmaceutical, Biotechnology, Medical Devices, or Life Sciences.
- Familiarity with Computer System Validation (CSV), GxP, and compliance requirements.
- Strong stakeholder management and communication skills with the ability to work effectively across global teams.
- Proven experience supporting MES implementations, go-live, hypercare, and production support environments.
- Ability to coordinate across business, quality, validation, infrastructure, and technical teams to deliver successful MES solutions.