Demo

Principal Mechanical Engineer II, Early Research and Development

Sharp Decisions
Santa Clara, CA Contractor
POSTED ON 4/14/2026
AVAILABLE BEFORE 10/12/2026
Senior Mechanical Engineer

A Medical Device Manufacturing / Pharmaceutical client of Sharp Decisions is seeking a Senior Mechanical Engineer in Santa Clara, CA. This is a 6-month contract with possible extension, offering $79.45/hour on a W2.

 

Job Description

This is a hands-on role for a multidisciplinary expert focused on solving core mechanical challenges for next-generation platforms. The role involves designing, building, and testing innovative electro-mechanical, pneumatic, thermal, and fluidic solutions to ensure system performance, reliability, and longevity.

The Principal Mechanical Engineer will drive innovation for next-generation instrumentation, requiring high motivation, independence, and resourcefulness in a fast-paced, collaborative environment.

Core Responsibilities
  • Lead end-to-end mechanical design and development of electro-mechanical, pneumatic, fluidic, and thermal sub-systems.
  • Collaborate with cross-functional engineering teams to define and manage technical interfaces.
  • Develop mechanisms for automated reagent and flow cell loading, clamping, and sealing.
  • Design and integrate thermal control systems including heating/cooling elements and sensors.
  • Partner with simulation teams to validate CFD, thermal, and optical models.
  • Serve as technical expert during system integration, verification, and troubleshooting.
  • Lead cross-functional design reviews and resolve technical trade-offs.
  • Manage timelines and deliverables for mechanical sub-systems.
  • Create and maintain detailed CAD models, drawings, and specifications.
  • Contribute to system architecture and technical strategy.
  • Present technical progress and engineering decisions to stakeholders.
Required Qualifications
  • PhD with 3 years, Master's with 4 years, or Bachelor's with 7 years of relevant experience.
  • Hands-on expertise in mechanical, electro-mechanical, and pneumatic system design.
  • Experience in thermal management and precision temperature control systems.
  • Experience with fluidics systems (pumps, valves, tubing, sensors).
  • Proficiency in 3D CAD tools (e.g., SolidWorks).
  • Experience with manufacturing processes (machining, injection molding, 3D printing).
  • Strong troubleshooting skills across hardware, software, and chemistry interfaces.
  • Experience with machine shop tools and rapid prototyping technologies.
  • Proficiency in Python, LabVIEW, or similar tools for device control and data acquisition.
Preferred Qualifications
  • Experience leading technical projects and mentoring engineers.
  • Experience with simulation tools such as CFD and FEA.
  • Experience with next-generation sequencing (NGS) or genomics instrumentation.
  • Experience in regulated product development environments.
  • Strong communication and interpersonal skills.
  • Ability to manage multiple priorities in a fast-paced environment.2

Salary : $79

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