What are the responsibilities and job description for the RCI-ABBV-35424 Scientist (Flow Cytometry/Mammalian Cell Culture/Assay Development/Antibody Characterization) position at Rangam?
Scientist II
Worcester, MA– onsite
1 year to start
- The Cell and Functional Biology team within Biotherapeutics Discovery is seeking a contract Scientist I/II to perform high-throughput binding and functional assays to drive and enable data-driven decisions for project and pipeline advancement.
- As a member of the Cell and Functional Biology team, primary role will focus on antibody characterization.
- The role includes executing and optimizing antibody screening funnel, cell line maintenance, data analyses, and standardization of protocols as related to automation.
Key Responsibilities:
- Maintain immortalized mammalian target overexpressing and native target expressing cell lines primarily; experience with primary cells beneficial but not required.
- Coordinate sourcing of internal and commercial reagents for screening assays.
- Utilize established high-throughput assay screening workflows for antibody binding, internalization, and potency characterization using automated liquid-handling systems.
- Execute and enable binding, internalization, and reporter assay experiments
- Analyze data for antibody binding specificity, internalization ability and potency using flow binding and assays platforms.
- Develop and standardize screening workflows, assay protocols, and automation procedures.
Qualifications
- Bachelor’s Degree or equivalent education with 5 years of relevant biotech or pharmaceutical industry experience, or master’s degree or equivalent education with two years of experience
- High-throughput screening experience and troubleshooting using Flow
- Strong understanding of screening workflows
- Perform cell culture under SOP GLP standards
- Prior experience and familiarity with protein-protein interaction, ELISA, target binding and functional cellular assays
- Excellent communication skills across broad audiences
- Ability to work effectively within internal, external and cross-functional teams
Salary : $48 - $49