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MES Engineer

Piper Companies
Piper Companies Salary
Springs, NC Full Time
POSTED ON 4/11/2026
AVAILABLE BEFORE 5/10/2026
Piper Companies is seeking an MES Engineer to join a large-scale life sciences manufacturing organization for a long-term onsite contract opportunity based in Holly Springs, North Carolina. This MES Engineer will support manufacturing execution system initiatives within a regulated pharmaceutical/biotechnology environment, contributing hands-on technical expertise to configuration, validation, and system readiness efforts across the site.

Responsibilities of the MES Engineer include:

  • Configure and support MES/Syncade solutions to meet site-specific manufacturing and quality requirements.
  • Lead technical setup activities, including system protocols, integration touchpoints, and environment readiness.
  • Perform and review code validation activities to ensure compliance with GMP and internal quality standards.
  • Partner with cross-functional teams to translate manufacturing needs into functional MES solutions.
  • Troubleshoot system issues and provide technical guidance during implementation and ongoing operations.

Qualifications for the MES Engineer include:

  • Five or more years of hands-on experience supporting MES platforms, with a strong preference for Syncade.
  • Prior experience in regulated pharmaceutical, biotech, or life sciences manufacturing environments.
  • Proven ability to independently handle technical configuration and validation without extensive ramp-up.
  • Strong understanding of system lifecycle documentation, protocols, and validation best practices.
  • Ability to work remotely with periodic onsite presence (approximately two weeks every two months).

Compensation for the MES Engineer:

Salary Range: $150,000-$170,000/year (USD)

Benefits eligibility dependent on employment arrangement

This job opens for applications on 4/10/26. Applications for this job will be accepted for at least 30 days from the posting date.

Keywords: MES, Syncade, manufacturing execution systems, pharmaceutical manufacturing, biotech, GMP, system validation, technical configuration, life sciences engineering, automation, quality systems, computer system validation, CSV, manufacturing IT, regulated manufacturing, process automation, system integration, remote engineering, hybrid engineering roles.

Salary : $150,000 - $170,000

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