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Supervisor- Antibody Purification Manufacturing

Job Opportunities
San Diego, CA Full Time
POSTED ON 3/23/2026
AVAILABLE BEFORE 4/22/2026

BioLegend develops world-class, cutting-edge antibodies and reagents for biomedical research, manufactured in our state-of-the-art facility in San Diego, CA. Our mission is to accelerate research and discovery by providing the highest quality products at an outstanding value, along with superior customer service and technical support. Our product expertise covers a diverse set of research areas including Immunology, Neuroscience, Cancer, Stem cells, and Cell Biology. 

Job Summary

The Purification Supervisor is responsible for managing all essential functions related to antibody purification. Candidate must have extensive knowledge of all purification processes and be capable of extensive trouble shooting. Must be able to train new employees on all purification processes, as well as ISO standards and company policies. Must be able to collaborate with other departments and create assignments, reports, and other data. Must be able to manage, coach, and develop a large department.

 

Essential Functions

Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

  • High Level understanding of IGG and IGM antibody protein structure and purification methods, antibody fragmentation, and antibody rework methods
  • Perform basic math calculations to calculate amount of antibodies
  • Prepare Buffers according to SOPs
  • Review SDS and IEF Gel electrophoresis
  • Expert with ERP system for management and manufacturing purposes
  • Expert in bulk order preparation
  • Train new employees on all purification processes
  • Extensive knowledge with troubleshooting issues in purification processes. Prepare data for weekly meetings. Responsible for opening and closing Non-conforming reports
  • Employee performance reviews and coaching and development
  • Recruiting new employees—resume review, interviews, selection
  • Create and edit SOPs and batch records
  • Ensure that department operates under ISO guidelines—train and enforce standards. Work with QA department to be trained and have complete understanding of ISO guidelines
  • Collaborate with multiple internal departments
  • Create weekly and monthly tasks to give to employees, as well as monthly reports to the manager
  • In charge of incoming raw materials from outside vendors—collaborate with Receiving Department to properly receive and manage OEM material 

Minimum Qualifications Education and Experience

  • BS degree in Biochemistry, Chemistry, or Science
  • 4-5 years relevant lab experience with column chromatography, gel electrophoresis (SDS-PAGE, IEF gel) or knowledge of other analytical or detection methods. Supervisory experience preferred 

Preferred Qualifications – Education and Experience 

  • Strong organizational, documentation, and interpersonal skills are essential. Must take initiative, be flexible, highly motivated, and dependable.  Good computer skills are a plus. Must be extremely detail-oriented. Great time management and multi-tasking skills

Condition of Employment

Concerns regarding COVID-19 continue as positive cases are experienced in the communities in which we operate. Please be aware that, as a condition of employment, BioLegend requires proof of COVID vaccination for all U.S.-based employees (subject to limited exceptions) beginning January 18, 2022.

Salary.com Estimation for Supervisor- Antibody Purification Manufacturing in San Diego, CA
$85,649 to $109,548
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