What are the responsibilities and job description for the Director Clinical Development position at i-Pharm Consulting?
Director/Senior Director, Clinical Development – Rheumatology
Location - open to candidates in:
- New York City
- Boston
- Research Triangle (NC) or
- San Francisco Bay Area
About the Opportunity
A technology-driven pharmaceutical company is seeking a board-certified physician with industry-based rheumatology clinical development and medical monitoring experience to serve as the clinical lead for their rheumatology pipeline. This high-impact role combines clinical expertise with cutting-edge innovation, including AI-enabled trial design and novel regulatory pathways.
The company reimagines drug development through innovative platforms, working to overcome traditional clinical trial bottlenecks and bring new medicines to patients faster. Backed by leading investors, they partner with biopharma companies to advance programs from proof of concept into later-stage development.
The Role
- Provide medical leadership for rheumatology programs, including a Phase II osteoarthritis asset currently in active FDA discussions.
- Shape AI-enabled trial designs, explore novel regulatory pathways, and drive innovative approaches to clinical development.
- Report directly to the Chief Medical Officer
- Short-term opportunity to directly lead a Clinical Scientist and clear potential to build a larger team as the rheumatology portfolio expands.
Key Responsibilities
Clinical Study Planning & Execution
- Develop protocol concepts, protocols, and clinical development plans
- Provide medical leadership during trial execution, including risk assessment and safety/efficacy oversight
- Serve as project physician for Phase 2–4 studies
Strategic Innovation
- Collaborate on AI-enabled clinical trial design and novel regulatory strategies
- Define innovative trial approaches with cross-functional expertise
- Drive process improvements and accelerated trial execution strategies
Business Development & Training
- Provide medical input on in-licensing and partnership opportunities
- Deliver clinical training for internal teams and trial sites
- Develop recruitment strategies to enhance enrollment efficiency
Qualifications
Required
- MD/DO with board certification in Rheumatology, Immunology, or Internal Medicine
- 1–3 years in biotech, pharma, or CRO
- Experience with protocol development, medical monitoring and medical oversight of Phase II-IV trials
Preferred
- Experience with regulatory interactions and contributions to filings
- First-principles thinking: questioning conventional approaches and identifying innovative solutions
- Comfort with technology-enabled drug development
- Aptitude for AI applications in clinical development
- Experience in smaller company environments/cultures
What This Role Offers
- High Visibility: Direct strategic influence in a small company environment
- Innovation Focus: Shape novel trial designs leveraging AI and cutting-edge regulatory pathways
- Growth Trajectory: Immediate leadership responsibility with potential to build a larger team
- Mission-Critical Impact: Central role advancing key pipeline assets through critical development milestones
Compensation & Benefits
- Base Bonus: $320,000 - $400,000
- Equity package
- Comprehensive benefits
Salary : $320,000 - $400,000