Scientist II – Histology (Ocular/Skin)

Responsibilities:

• Excellent employment opportunity for a Scientist II in the Ridgefield, CT area.
• Execute tissue processing to prepare high-quality samples for analysis, ensuring consistency and adherence to established protocols.
• Conduct tissue embedding using paraffin and frozen section techniques to enable accurate sectioning and downstream applications.
• Perform tissue staining, including immunohistochemistry (IHC), immunofluorescence (IF), and histological staining, to support imaging and research goals.
• Troubleshoot and optimize protocols to ensure reproducible, high-quality results.
• Collaborate with researchers to design experiments, analyze data, and interpret findings.
• Maintain detailed records of procedures, results, and inventory in compliance with laboratory standards.

Experience:

• Master's degree in biology, biomedical sciences, or a related field (bachelor's degree with significant relevant experience may be considered).
• Experience: 3-5 years of hands-on experience in tissue processing, tissue staining, and tissue embedding in a research or clinical laboratory setting.
• Proficiency in histological techniques, including paraffin and cryosectioning.
• Expertise in IHC, IF, and other histological staining methods.
• Ability to troubleshoot and optimize tissue preparation protocols.
• Analytical Skills: Strong attention to detail and ability to analyze and interpret experimental data.
• Organizational Skills: Excellent time-management and multitasking abilities to handle multiple projects efficiently.
• Clear written and verbal communication for collaborating with researchers and documenting procedures.
• Teamwork: Ability to work both independently and collaboratively in a team-oriented research environment.
• Compliance: Familiarity with laboratory safety protocols and quality control standards.

Preferred Domain Expertise (Ocular or Skin Focus Required)

Candidates must have a primary focus in either ocular or dermatology-related research.

Ocular (Ophthalmology) Experience – Preferred:

• Retinal tissue handling and analysis
• Experience with eye injections (including animal models)
• Exposure to ophthalmology research programs
• Familiarity with anti-VEGF studies

OR

Skin (Dermatology) Experience – Preferred:

• Subcutaneous dosing techniques
• Experience with transdermal delivery systems
• Dermal penetration or permeability assays
• Skin biopsy analysis following dosing

Core Technical Qualifications

Candidates should demonstrate experience in at least 5–6 of the following areas:

• Tissue processing (paraffin embedding, frozen sections)
• Histological staining, including IHC and IF
• Drug delivery and/or in vivo dosing studies
• Skin or ocular tissue exposure models
• Formulation, delivery routes, or penetration studies
• PK/PD analysis or efficacy readouts
• Collaboration with DMPK or drug delivery teams
• Support of translational or clinical research programs