Demo

Senior Scientist

BioTalent
Durham, NC Full Time
POSTED ON 10/28/2026
AVAILABLE BEFORE 11/26/2026

We're partnering with an innovative oncology biotech seeking a Senior Scientist to help advance a pipeline of targeted cancer therapies. This is a hands-on, laboratory-based role focused on elucidating drug efficacy and mechanism of action, with a particular emphasis on receptor tyrosine kinase (RTK) biology, ideally HER2.


This position offers the opportunity to play a key role in discovery research, generating critical data that informs program strategy and supports the advancement of novel oncology therapeutics.


The Opportunity

As part of a collaborative research team, you will:

  • Design and execute in vitro efficacy, mechanism of action, target validation, and biomarker studies for oncology programs
  • Apply deep expertise in RTK signaling biology, with a preference for HER2-focused experience
  • Manage and maintain cancer and normal cell culture models
  • Generate engineered cell lines using CRISPR and inducible expression systems
  • Develop and optimize reporter-based assays and cellular models
  • Analyze and communicate scientific findings to internal stakeholders and external audiences
  • Contribute to conference abstracts, scientific publications, and other research communications
  • Establish robust experimental workflows, documentation practices, and troubleshooting procedures
  • Support multiple research programs within a fast-paced, collaborative environment


What We're Looking For

  • PhD in Cancer Biology, Molecular Biology, Cell Biology, Biochemistry, Pharmacology, or a related discipline (Master's degree with significant relevant experience will also be considered)
  • 3 years of industry and/or postdoctoral experience in oncology research
  • Demonstrated expertise in receptor tyrosine kinase biology, ideally including HER2 signaling and targeted therapies
  • Strong background in oncology pharmacology assays and mechanistic biology studies
  • Experience developing and characterizing cellular models, including CRISPR-engineered systems
  • Track record of scientific communication through publications, presentations, or conference abstracts
  • Ability to manage multiple projects simultaneously with minimal supervision
  • Strong organizational skills and attention to detail
  • Excellent written and verbal communication skills
  • Experience working effectively in a cross-functional, matrixed environment


This is an excellent opportunity to join a growing biotechnology company where you'll have the chance to make a meaningful scientific impact while helping to advance next-generation therapies for patients with cancer.


To learn more, please get in touch directly.


#BiotechJobs #Oncology #CancerBiology #DrugDiscovery #PharmaceuticalResearch #LifeSciences #Biotechnology #ScientistJobs #CancerTherapeutics #HER2 #RTK #CRISPR

Salary : $120,000 - $170,000

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