Demo

Principal Engineer

BEPC Inc. - Business Excellence Professional Consulting
St Louis, MO Contractor
POSTED ON 6/21/2026
AVAILABLE BEFORE 7/19/2026

Job Title: General Engineering & Skilled Trade Project Manager 5

Location: Saint Louis, MO 63103

Employment Type: W2 Contract – 12 Months with the Possibility of Extension

Shift: Standard Business Hours

Work Model: Fully Onsite

Role Overview

BEPC is seeking a highly experienced Principal Engineer to support a major pharmaceutical manufacturing expansion project in Saint Louis, MO. This role will provide senior-level project engineering leadership for large-scale capital projects within a regulated life sciences environment.

The ideal candidate will have extensive experience leading pharmaceutical or biotechnology facility projects, including cleanroom construction, brownfield expansions, facility qualification, and validation activities. This position requires strong technical expertise, stakeholder management skills, and the ability to independently drive project execution from planning through completion.

Key Responsibilities

Provide senior-level project engineering leadership for complex capital projects.

Lead project workstreams and ensure successful execution within scope, budget, and schedule requirements.

Collaborate with site, engineering, construction, and project teams to support timely project decisions.

Identify, assess, and mitigate project risks while implementing effective solutions.

Manage stakeholder communications and maintain alignment across project teams.

Review engineering drawings, specifications, and technical documentation.

Support cleanroom design, construction, qualification, and validation activities.

Review and respond to construction submittals, RFIs, and scope change requests.

Develop and maintain project schedules, documentation, and workstream deliverables.

Ensure compliance with pharmaceutical manufacturing regulations, industry standards, and cGMP requirements.

Drive issue resolution while balancing safety, quality, budget, schedule, and operational objectives.

Provide technical guidance and leadership throughout project execution.

Required Qualifications

Bachelor of Science degree in Engineering required.

Minimum of 15 years of experience in capital project execution and construction-related engineering roles.

Experience supporting pharmaceutical, biotechnology, or life sciences manufacturing facilities.

Experience leading cleanroom construction, classified spaces, and facility qualification projects.

Strong understanding of pharmaceutical manufacturing regulations, industry standards, and cGMP requirements.

Ability to interpret engineering drawings, specifications, and technical documentation.

Proven experience managing project schedules, budgets, risks, and stakeholder expectations.

Strong leadership, communication, negotiation, and relationship-building skills.

Ability to influence decision-making in a matrixed project environment.

Experience reviewing construction submittals, RFIs, and scope changes.

Ability to independently manage complex project workstreams and deliverables.

Preferred Qualifications

Brownfield pharmaceutical facility expansion experience.

Process engineering background.

Experience supporting facility qualification and validation activities.

Experience managing large-scale manufacturing expansion projects.

Knowledge of engineering design, construction management, and commissioning processes.

Experience working within highly regulated pharmaceutical manufacturing environments.

About BEPC

BEPC Inc., founded in 2007, is a 100% employee-owned company providing top-tier consulting and staffing solutions across industries like technology, engineering, manufacturing, and project management. At BEPC, we are driven by innovation and a commitment to excellence. We take pride in fostering a collaborative and innovative environment where our team members thrive.

Apply Now!

Qualified candidates are encouraged to submit an up-to-date resume highlighting pharmaceutical manufacturing, capital project execution, cleanroom construction, facility expansion, engineering leadership, and project management experience. Please include specific examples demonstrating your success leading complex engineering projects within regulated life sciences environments.

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