Janssen Research & Development, L.L.C., a division of Johnson & Johnson's Family of Companies, is recruiting for a Principal Scientist, Computer-Aided Drug Design (CADD, Computational Chemistry) located in San Diego, CA (La Jolla area).

At the Janssen Pharmaceutical Companies of Johnson & Johnson, we work to create a world without disease. Transforming lives by finding new and better ways to prevent, intercept, treat and cure disease inspires us. We bring together the best minds and pursue the most promising science. We collaborate with the world for the health of everyone in it. Learn more at www.janssen.com and follow us @JanssenGlobal. Janssen Research & Development, LLC is part of the Janssen Pharmaceutical Companies.
At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com/.

The Therapeutics Discovery organization within Janssen R&D is continuing to build scientific expertise in modeling, screening, pharmacology and chemistry to partner closely with therapeutic area scientists to develop groundbreaking new medicines in the areas of Immunology, Neuroscience and Oncology. The In Silico Discovery (ISD) group in Therapeutics Discovery is seeking excellent scientists to bring their expertise to exciting and novel areas of computational drug design.

Key Responsibilities Include:

• Shape and implement computational strategies to support innovative modality-agnostic drug discovery at Janssen R&D by researching and incorporating new physics-based and AI/ML techniques and platforms
• Develop and grow the CADD/ISD team at Janssen by mentoring, managing and recruiting other group members
• Design therapeutic molecules and calculate their properties using state-of-the-art methodologies integrating chemical, biological and structural data, cheminformatics, and artificial intelligence/machine learning techniques
• Represent In Silico Discovery in governance forums and external collaborations; publish results in peer reviewed journals and present at scientific meetings
• Serve as a scientific expert with both internal and external partners, and provide recommendations regarding new targets and emerging external opportunities
• Ensure optimal interaction/communication and provide updates on project status to discovery leadership