Description

About iBio

iBio is an AI-driven innovator that develops next-generation biopharmaceuticals using computational biology and 3D-modeling of subdominant and conformational epitopes, prospectively enabling the discovery of new antibody treatments for obesity, cardiometabolic, hard-to-target cancers, and other diseases. iBio’s mission is to decrease drug failures, shorten drug development timelines, and open up new frontiers against the most promising targets. iBio is based in San Diego, CA. For more information, visit www.ibioinc.com.

The Opportunity

iBio is excited to announce a new opportunity for a Bioinformatics Scientist to join our world-class Platform team in Sorrento Valley, San Diego. As a Bioinformatics Scientist, you will be responsible for executing iBio’s core machine learning engine and designing experiments to test model performance in the wet lab. Your background in programming will be critical for building bioinformatics tools and pipelines for antibody drug discovery campaigns. You will then put your predictive models to the test through wet lab experiments.

The successful candidate will leverage cross-disciplinary expertise in computation and biology to support antibody drug discovery efforts in both internal campaigns as well as external partnerships. Antibodies that bind desired epitopes will be efficiently discovered using our patented Engineered Epitopes protein structural design platform. Additionally, antibody optimization libraries will be designed using machine learning language models trained on public and internal datasets. Antibodies will then be screened for antigen and epitope binding by mammalian display and single cell sorting, generating datasets that feed back into models for additional learning.

This role is located in San Diego, CA.

Responsibilities:

• Execute bioinformatics analysis and pipelines for antibody drug discovery
• Computationally design engineered proteins for discovery of epitope-specific antibodies
• Computationally design antibody libraries to optimize template antibodies
• Construct antibody libraries using standard cloning techniques
• Produce and purify proteins using mammalian and E. coli expression systems
• Document and organize data in an electronic lab notebook

Requirements

• PhD in Bioinformatics, Computational Biology, Biophysics, Physics, or related life sciences and computational field. OR
• MS/MA in Bioinformatics, Computational Biology, Biophysics, Physics, or related life sciences and computational field and 3 years of biotech/pharmaceutical industry experience. OR
• BS/BA in Bioinformatics, Computational Biology, Biophysics, Physics, or related life sciences and computational field and 5 years of biotech/pharmaceutical industry experience.
• Proficiency in programming languages such as Python, R, Java, or C
• Proven track record of developing bioinformatics and/or computational biology tools and algorithms
• 1 year of experience modeling protein and/or DNA sequence data
• Experience with basic wet lab techniques
• Excellent organization and communication skills
• Proven track record of collaborating with cross-functional teams

Preferred skills:

• Experience designing and executing molecular biology is a plus
• Experience with protein purification and/or functional assays is a plus

California Base Salary Range

The expected annual base salary for this position ranges from $85,000.00 to $115,000.00, plus bonus, equity, and comprehensive benefits. The base salary range reflects the target range for this position, but individual pay will be determined by various factors, including the qualifications of the individual applicant for the position, years of relevant experience, job-related skills, relevant education attained, work location, and organizational needs. This range may be modified in the future. A discretionary annual bonus may be available based on individual and Company performance.

All qualified applicants are considered for employment without regard to race, color, religion, age, sex, sexual orientation, gender identify, national origin, disability, veteran status or other protected classes.

What do we offer?

We provide competitive and comprehensive benefits to our employees. Below are some highlights of our benefits:

• Medical, Dental, and Vision Insurance Options
• Flexible Time Off
• Our company observes seven designated holidays each calendar year. 
• 401(k) with Company Match as described in plan documents.
• Life and Disability Insurance
• Short-term and long-term disability insurance

EEO Statement

iBio is proud of its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability, or any other legally protected status.

iBio is committed to helping individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at iBio, please email ibio_peopleculture@ibioinc.com for further assistance. Please note that this email address is intended only to request an accommodation as part of the application process. Any other correspondence will not receive a response. 

Notice to Recruiters

Thank you for your interest in iBio and our recruitment opportunities. Recruiting and employment are managed through the Human Resources Department. iBio requires a signed agreement be in place prior the presentation of any candidates. We ask that recruiters and agencies do not contact or solicit employees or managers in an attempt to present candidates. iBio will not be obligated or responsible for any requested fees to candidate resumes that are unsolicited and or submitted to hiring managers without a written agreement between iBio and any recruiters and agencies.