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Senior Scientist 3/ Principal Scientist, Analytical Chemistry

Ginkgo BioWorks

Boston, MA | Full Time

$109k-136k (estimate)

6 Days Ago

Senior Data Scientist, Statistical Genetics

Valo Health

Boston, MA | Full Time

$125k-153k (estimate)

6 Days Ago

Senior Scientist 3/ Principal Scientist, Analytical Chemistry

$109k-136k (estimate)

Full Time 6 Days Ago

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Ginkgo BioWorks is Hiring a Senior Scientist 3/ Principal Scientist, Analytical Chemistry Near Boston, MA

Our mission is to make biology easier to engineer. Ginkgo is constructing, editing, and redesigning the living world to answer the globe’s growing challenges in health, energy, food, materials, and more. Our bioengineers make use of an in-house automated foundry for designing and building new organisms.

To realize our dream of building a next-generation organism company, we must ensure that quality is maintained during all stages of our projects, through to the successful deployment of our organisms and processes. Therefore, we’re looking for a team member with strong analytical chemistry experience to develop, manage and interpret assay quality specifications for a wide range of procedures and analytes. As a Senior Scientist 3 or Principal Scientist, Analytical Chemistry, you will be a key contributor of the QAQC team that will help to design and deploy analytical capabilities for proteins and other large-molecule analytes. You’ll help ensure that Ginkgo, our customers, and our contract manufacturers have the necessary methods and processes in place so that we maintain compliance across any required regulatory standard and consistently meet the defined product and process specifications. Support of building policies and structures that allow for scalability and are aligned internally with Foundry operations will also be integral part of the position.

Responsibilities

Develop, validate and transfer sample preparation and analytical quantification methods for chemical and biological analytes within upstream and downstream fermentation samples using analytical methods such as LC-UV, GC-FID, IC-PAD, CGE, LC-HRMS, and GC-MSMS
Support project specific QAQC to ensure that criteria, application and decision making are aligned with standards as defined by Ginkgo’s Quality team
Support incoming and outgoing analytical method transfers, including method alignment, method validation, standard operating procedure (SOP) generation and equivalence testing
Supporting lab scale through pilot scale activities within Ginkgo and interfacing with tech transfer to and from customers
Aligning organizational objectives with department strategy; support translation of strategic decisions into effective short- and long-term planning including staffing, development and scientific initiatives
Create, manage and analyze control charts which monitor accuracy and precision of analytical QAQC procedures over time to streamline quality assurance, secondary review of data and root cause analysis
Design, revise and deploy structured systems to streamline and encourage scalability of current QAQC processes (processes are described in below responsibilities)
Perform QAQC data collection, integration, analysis, and reporting with the use of Ginkgo’s proprietary laboratory information management system (LIMS), driving revision of the LIMS when necessary
Maintain analytical instrumentation and associated maintenance logs, troubleshooting instruments as needed

Desired Experience and Capabilities

BS in analytical chemistry or related field with at least 10 years of industrial experience; Or Ph.D. with at least 5 years of industrial experience
Experience in leadership within analytical method development and analytical tech transfer in the context of large-molecule applications
Strong expertise in operating and maintaining chromatographic analytical chromatography equipment, especially LC-UV, GC-FID, IC-PAD, CGE, LC-HRMS, and GC-MSMS - experience with CGE would be a plus
Strong hands-on knowledge and experience in purification and analyses of proteins and large molecules would be a plus
Experience creating, tracking and analyzing control charts for quality assurance and streamlined root cause analysis
Ability to design systems that streamline and scale analytical testing processes
Demonstrated mastery of authoring SOPs, validation reports, and certificates of analysis (COAs)
Expertise in Chromeleon, 32 Karat and/or Empower is highly desirable
Ability to work well within a fast-paced team environment and balance multiple projects simultaneously with excellent communication
Excellent presentation and communication skills and the ability to communicate with technical and non-technical audiences
Strong hands-on knowledge and experience in purification and analyses of proteins would be a plus

To learn more about Ginkgo, check out some recent press:

What is it really like to take your company public via a SPAC? One Boston biotech shares its journey (Fortune)

Ginkgo Bioworks resizes the definition of going big in biotech, raising $2.5B in a record SPAC deal that weighs in with a whopping $15B-plus valuation (Endpoints News)

Ginkgo Bioworks CEO on scaling up Covid-19 testing: ‘If we try, we can win’ (CNBC)

Ginkgo raises $70 million to ramp up COVID-19 testing for employers, universities (Boston Globe)

Ginkgo Bioworks Redirects Its Biotech Platform to Coronavirus (Wall Street Journal)

Ginkgo Bioworks Provides Support on Process Optimization to Moderna for COVID-19 Response (PRNewswire)

The Life Factory: Synthetic Organisms From This $1.4 Billion Startup Will Revolutionize Manufacturing (Forbes)

Synthetic Bio Pioneer Ginkgo Raises $290 Million in New Funding (Bloomberg)

Ginkgo Bioworks raises $350 million fund for biotech spinouts (Reuters)

Can This Company Convince You to Love GMOs? (The Atlantic)

We also feel that it’s important to point out the obvious here – there’s a serious lack of diversity in our industry, and that needs to change. Our goal is to help drive that change. Ginkgo is deeply committed to diversity, equity, and inclusion in all of its practices, especially when it comes to growing our team. Our culture promotes inclusion and embraces how rewarding it is to work with people from all walks of life.

We’re developing a powerful biological engineering platform, so we must remain mindful of the many ways our technology can – and will – impact people around the world. We care about how our platform is used, and having a diverse team to build it gives us the best chance that it’s something we’ll be proud of as it continues to grow. Therefore, it’s critical that we incorporate the diverse voices and visions of all those who play a role in the future of biology.

It is the policy of Ginkgo Bioworks to provide equal employment opportunities to all employees and employment applicants.