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Research Associate I

University of Massachusetts and Careers
Worcester, MA Full Time
POSTED ON 4/9/2026
AVAILABLE BEFORE 3/30/2027
Overview:
POSITION SUMMARY:

Under the direction of the Principal Investigator (PI) or designee, the Research Associate I provides operational support to the laboratory. The Research Associate I will perform research experiments as defined by the PI.

The Li lab is recruiting a Research Associate to perform nucleic acid chemistry to support research projects related to mRNA therapeutics and the Sponsor Research Agreement with Rhodes Therapeutics. The research projects will involve solid-phase nucleic acid synthesis, organic synthesis, LC-MS analysis, NMR, reverse-phase chromatography, and other purification techniques. A bachelor's degree in chemistry is required.

Li lab works on developing platform technologies for mRNA therapeutics. We utilize a wide
range of technologies including biochemistry, chemical biology, directed evolution, and
high-throughput sequencing.

Responsibilities:
ESSENTIAL FUNCTIONS:

  • Perform laboratory experiments and may be responsible for a single research project
  • Utilize all software relevant to experiment and equipment used
  • Interpret data, form conclusions and decide on next steps under the direction of the PI or designee
  • Maintain accurate records, may modify protocols with the approval of the PI or designee
  • Review literature, publications and grants relevant to assigned projects
  • Record results according to established lab, sponsor & university protocol
  • Assist with performing data analysis and/or mathematical computations
  • Maintain a detailed lab notebook according to lab practice
  • Present findings at lab/group meetings
  • Monitor laboratory supply levels and order as noted
  • Prepare and label buffers, media, solutions, etc.
  • Assist with and comply with all safety regulation and infection control standards
  • Train on IACUC, IRB, EHS, Radiation safety protocols
  • Comply with all applicable state, federal university, and sponsor policies and agreements
  • Provide support with identifying problems and challenges, propose resolutions, implement appropriate solutions
  • Provide support with drafting standard operation procedures in compliance to EHS regulation specific for the lab
  • Perform other duties as required
Qualifications:
REQUIRED QUALIFICATIONS:

  • Bachelor’s degree in Biological or Natural Science, or equivalent experience
  • Basic understanding of lab safety and protocols
  • Knowledge of Microsoft Office products
  • Ability to analyze data in a quantitative and objective manner.
  • Ability to work in a team environment

Salary : $40,000 - $43,000

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