What are the responsibilities and job description for the Postdoctoral Scholar position at University of Chicago?
The ovarian cancer research laboratory at the University of Chicago, led by Drs. Hilary Kenny and Ernst Lengyel (PIs), is seeking two postdoctoral fellows with expertise in bottom-up proteomics to advance plasma proteomics research and spatial proteomics (DVP).
Plasma Proteomics Project: This project aims to establish MS-based plasma proteomic methods capable of distinguishing between benign and malignant ovarian diseases. The ultimate objective is to identify and validate reliable biomarkers to support clinical decision-making, including early detection of tumor recurrence and assessment of chemotherapy response.
Spatial Proteomics Project: This project aims to use LC/MS-based spatial proteomics (DVP) capable of identifying the origins, development, and response to standard and novel therapy treatment in ovarian cancer patients. The ultimate objective is to identify the origin of different ovarian cancers and effective therapies for individual ovarian cancer patients.
The projects involve active collaboration with the Matthias Mann Lab in Munich, and these projects are integrated within a multidisciplinary translational clinical team.
The laboratory is equipped with cutting-edge instruments (e.g. Orbitrap Astral Zoom, EvoSep One, FAIMS, LMD7) and a large collection of clinically annotated samples, providing a strong foundation for the success of these projects. The University of Chicago Comprehensive Cancer Center includes more than 150 funded researchers dedicated to exploring all facets of cancer biology. The position offers a competitive salary, extensive fringe benefits (included supplement for health insurance and retirement) and a structured career development program.
Job Requirements
- PhD in biochemistry, molecular biology, analytical chemistry, bioinformatics or related discipline/field
- Minimum 2-3 years of hands-on experience with LC-MS/MS systems
- Collaborative mindset and the ability to work independently and as part of a team
- Strong academic background with a publication record in peer-reviewed journals
- Excellent written and oral communication skills
- Experience: Proteomics mass spectrometry and proteomics, sample preparation, including working with plasma or tissue samples, bioinformatics/data analysis tools and experimental design
- Experience: Proteomics mass spectrometry, sample preparation, bioinformatics/data analysis tools and experimental design
https://obgyn.uchicago.edu/research/lengyelkenny-ovarian-cancer-laboratory
Interested candidates should send a CV and email to: lengyeloffice@bsd.uchicago.edu