Demo

Director of Bioinformatics

Trailhead Biosystems Inc.
Beachwood, OH Full Time
POSTED ON 7/27/2026
AVAILABLE BEFORE 11/24/2026

About Us

Trailhead Biosystems merges developmental biology with computerized experimental design to develop novel iPSC research products. Trailhead Biosystems is the pioneer of High-Dimensional Design-of-Experiment (HD-DoE®), a powerful platform that differentiates human induced pluripotent stem cells (iPSCs) into virtually any desired cell type with unparalleled precision and efficiency. We are moving beyond traditional trial-and-error methods by implementing Quality by Design principles and utilizing DoE combined with Multivariate Data Analysis.

The Role

We are seeking a Director of Bioinformatics & AI Engineering (iPSC Platform) to join our team and help define the future of product development and cellular engineering. As a Director of Bioinformatics & AI Engineering (iPSC Platform), you will lead a team consisting of Computational Biology, AI Engineering, and Database Engineering. You should have a deep understanding of Design of Experiment, as well as a strong grasp of machine learning & artificial intelligence tools and technology trends.

Responsibilities

  • HD-DoE platform: overall ownership of the HD-DoE platform, including experimental design and modelling, as well as maintenance of SOPs, training, and equipment to maintain a steady workflow of HD-DoE experiments
  • Molecular Biology: oversee analysis of all bulk and single cell RNA-sequencing, whole genome sequencing, and ATAC-seq
  • Leadership: manage a team of Analysts, Data Scientists & Engineers to meet short- and long-term goals related to integrating AI into the HD-DoE platform
  • Experimental validation of models: partner closely with dedicated Scientist to generate training data and validate AI-generated predictions at the bench
  • Cross-Functional Collaboration: Partner closely with R&D Scientists and Product Managers to ensure the HD-DoE platform meets the company's needs for product development and marketing
  • Documentation: Create and maintain clear technical documentation, architecture diagrams, and runbooks to ensure system reproducibility and facilitate team knowledge sharing

Qualifications & Requirements

  • MSc or PhD (preferred) degree in Bioinformatics, Computational Biology or a related quantitative field
  • 5 years of professional experience in analyzing large biological datasets
  • 2 years of experience in biotechnology, pharmaceutical, or healthcare sectors
  • Leadership experience including direct supervision of technical staff
  • Ability to translate complex technical concepts for cross-functional teams, including biologists and lab scientists
  • Collaborative spirit with a desire to work in a fast-paced, research-driven environment

Pay: $155,000.00 - $175,000.00 per year

Benefits:

  • 401(k)
  • 401(k) matching
  • Dental insurance
  • Health insurance
  • Life insurance
  • Paid time off
  • Parental leave
  • Referral program
  • Vision insurance

Work Location: In person

Salary : $155,000 - $175,000

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