Demo

Clinical Research Nurse

TalentCraft
Chicago, IL Contractor
POSTED ON 4/17/2026
AVAILABLE BEFORE 5/16/2026
  • 100% onsite in Chicago, IL
  • Contract to hire position
  • Current Illinois RN license required


Job Summary

The Clinical Research Nurse is a licensed nurse who provides care to research participants while supporting clinical studies under a Principal Investigator (PI). This role assists with recruitment, screening, consent, and protocol adherence, monitors participant health, manages adverse events, and administers study treatments as needed. The CRN collaborates with the research team, educates staff on protocols, and communicates participant updates.


This entry-level role requires strong nursing fundamentals, attention to detail, and the ability to learn research regulations and work with diverse teams.


Responsibilities:

Patient Care & Communication

  • Deliver protocol-driven care, monitor participant status, and document findings
  • Communicate updates to participants, families, and care teams
  • Escalate changes in participant condition to PI/team
  • Educate staff on study protocols

Clinical & Research Operations

  • Perform study procedures (assessments, medication administration, sample collection)
  • Schedule visits, prepare materials, and maintain accurate documentation
  • Enter and manage study data in systems (e.g., OnCore, REDCap, Epic)
  • Coordinate specimen handling and ensure regulatory compliance
  • Identify and report adverse events, deviations, or documentation issues

Coordination & Execution

  • Review eligibility and support participant recruitment
  • Track study timelines and ensure protocol compliance
  • Support audits, monitoring, and financial documentation

Team Support

  • Participate in study meetings and assist with onboarding new staff
  • Support regulatory submissions and documentation as needed


Qualifications:

Required

  • BSN or MSN
  • 2 years clinical nursing experience
  • Active Illinois RN license
  • BLS certification

Preferred

  • 2 years of clinical research experience
  • Relevant specialty certification

Key Skills

  • Basic knowledge of clinical research regulations (GCP/GDP)
  • Strong communication and organizational skills
  • Attention to detail and critical thinking
  • Ability to collaborate across teams and engage participants

Salary : $40 - $55

If your compensation planning software is too rigid to deploy winning incentive strategies, it’s time to find an adaptable solution. Compensation Planning
Enhance your organization's compensation strategy with salary data sets that HR and team managers can use to pay your staff right. Surveys & Data Sets

What is the career path for a Clinical Research Nurse?

Sign up to receive alerts about other jobs on the Clinical Research Nurse career path by checking the boxes next to the positions that interest you.
Income Estimation: 
$85,059 - $105,958
Income Estimation: 
$60,404 - $76,911
Income Estimation: 
$85,059 - $105,958
Income Estimation: 
$60,404 - $76,911
Employees: Get a Salary Increase
View Core, Job Family, and Industry Job Skills and Competency Data for more than 15,000 Job Titles Skills Library

Job openings at TalentCraft

  • TalentCraft Dubuque, IA
  • JOB SUMMARY A Clinical Research Assistant is an entry-level research position. This position is responsible for performing a variety of duties including co... more
  • 9 Days Ago

  • TalentCraft Champaign, IL
  • JOB SUMMARY The Clinical Research Manager oversees the day-to-day operations and execution of clinical trials at a specific site. They manage all aspects o... more
  • 13 Days Ago

  • TalentCraft Agawam, MA
  • Job Title : Quality Control Technician Overview Summary: Our client is seeking a highly skilled and detail-oriented Quality Control Technician III to suppo... more
  • 15 Days Ago

  • TalentCraft Bloomingdale, IL
  • Job Title: Welder II Overview summary Seeking a skilled Welder II to perform manual welding operations to manufacture weldments according to defined specif... more
  • 1 Day Ago


Not the job you're looking for? Here are some other Clinical Research Nurse jobs in the Chicago, IL area that may be a better fit.

  • WEP Clinical Chicago, IL
  • Are you a skilled, compassionate nurse looking for flexible work in clinical research? As a Clinical Research Nurse – Home Visits (PRN), you’ll provide hig... more
  • 24 Days Ago

  • Worldwide Clinical Trials Chicago, IL
  • Who we are We’re a global, midsize CRO that pushes boundaries, innovates and invents because the path to a cure for the world’s most persistent diseases is... more
  • 23 Days Ago

AI Assistant is available now!

Feel free to start your new journey!