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Senior Director of Facilities

Soufflé Therapeutics
Watertown, MA Full Time
POSTED ON 8/2/2026
AVAILABLE BEFORE 8/31/2026

Soufflé Therapeutics | Senior Director, Facilities | Job Description


Soufflé Therapeutics is a biotech company focusing on the cell-type specific delivery of genetic medicines. It's team of driven scientists is making a mark in delivery of oligonucleotides to extrahepatic tissues. We thrive in a purpose-building lab and office space in Watertown. Come and join us in our quest!


Position Summary:

Soufflé is seeking a Senior Director, Facilities to own real estate strategy, lab and space planning, and safe, efficient operations across our growing Watertown and Dresden footprint. As we add a new floor and plan for continued growth beyond 2027, this leader will build the systems, processes, and safety culture needed to scale — partnering closely with functional leads across the company.


Key Responsibilities

  • Lead and own strategy, implementation, and performance across Soufflé's real estate, including both lab and office operations, safety, and security
  • Lead lab and space planning, including capital projects, to support the company's growth
  • Engage key stakeholders to implement and integrate systems and processes for efficient, safe lab operations
  • Build a strong safety and quality culture
  • Act as a hands-on team player in a highly integrative role, mentoring direct reports


What Success Looks Like

  • In 3 months: Actively leading space expansion discussions and planning
  • In 6 months: Lab and office expansions managed to schedule, with key systems and processes rolled out
  • In 12 months: Strategy defined for the next stage of growth


Qualifications — Required

  • 10 years of facilities/lab operations leadership experience, including 4 years in a similar lead role
  • Experience at 150-400 employee stage companies with chemistry, biology lab, and vivarium environments
  • Experience in Biotech and/or pharma
  • Hands-on leadership style; leads by example and engages stakeholders effectively through new systems and process roll-outs


Qualifications — Preferred

  • Experience in construction project management and permitting; strong knowledge of HVAC, utilities, and biologics/chemical production facility requirements;
  • Experience across multiple/international sites


Education

  • Bachelor's degree required; advanced degree a plus


At Soufflé Therapeutics, we are intentional about building an equitable culture. How we treat our people is reflective of this focus. This is an onsite position in Watertown, MA (US) with flexibility as needed for collaboration and external engagements.

We are an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees

Salary.com Estimation for Senior Director of Facilities in Watertown, MA
$188,278 to $237,234
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