Head of Manufacturing

About SiPhox Health

SiPhox Health is building a next-generation, silicon-photonics–based blood testing platform that brings advanced clinical diagnostics into the home. Our technology integrates precision optics, microfluidics, and immunoassay chemistry into a compact system capable of generating laboratory-quality biomarker results from a small capillary blood sample.

We are now building the manufacturing engine behind this platform, from early production through scale.

The Role

We are looking for a Head of Manufacturing to build and lead our manufacturing organization from the ground up.

This is not a maintenance role, it is a systems-building role. You will define how we produce, how we scale, and how we maintain quality and speed simultaneously.

You will own everything from early production workflows to multi-shift operations, working closely with engineering to translate a complex, high-precision product into a robust and scalable manufacturing system.

What You’ll Do

Build the Manufacturing System

• Design and implement end-to-end manufacturing processes for cartridges and instruments
• Define production workflows, line layouts, and capacity planning
• Establish scalable assembly processes for microfluidics, optics, and reagent systems

Stand Up Operations

• Build and lead the manufacturing team (operators, technicians, leads)
• Establish shift structures, training systems, and operational discipline
• Create a high-performance, accountable production culture

Drive Throughput & Scale

• Own output, yield, and cost targets
• Identify and remove bottlenecks across the production flow
• Scale from early builds to sustained, high-throughput manufacturing

Quality & Systems

• Implement structured manufacturing practices aligned with regulated environments (GMP, ISO 13485)
• Build documentation systems (SOPs, work instructions, traceability)
• Partner with Quality and Engineering on validation, verification, and process control

Cross-Functional Leadership

• Work closely with Hardware, Assay, and Systems Engineering teams
• Translate evolving product designs into manufacturable processes
• Provide feedback to improve design for manufacturability (DFM)

Supply Chain & Materials

• Oversee materials flow, inventory strategy, and supplier coordination
• Ensure production readiness through disciplined planning and forecasting

What We’re Looking For

Required

• 7 years experience in manufacturing, with significant time in a leadership role
• Proven track record of building or scaling manufacturing operations
• Strong understanding of process development, yield improvement, and throughput optimization
• Hands-on mindset—you can go from strategy to the floor and back

Preferred

• Experience in medical devices, biotech, semiconductor, or other high-precision manufacturing
• Familiarity with microfluidics, optics/photonics, or cartridge-based systems
• Experience scaling from prototype/low-volume to production
• Experience in regulated environments (GMP, ISO 13485)

What Success Looks Like

• A manufacturing system that is repeatable, scalable, and disciplined
• A team that can execute with speed and precision
• Clear visibility into yield, throughput, and cost drivers
• The ability to scale without chaos

Why Join SiPhox?

• Build the manufacturing backbone of a category-defining diagnostics company
• Work at the intersection of photonics, microfluidics, and biotechnology
• Join at a stage where your decisions shape the company for years to come
• Grow into a senior leadership role as the company scales

Benefits:

• 401(k)
• Dental insurance
• Health insurance
• Health savings account
• Life insurance
• Paid time off
• Parental leave
• Vision insurance

Work Location: In person