Demo

Principal Investigator – Clinical Research

QPS Holdings, LLC
Springfield, MO Full Time
POSTED ON 7/9/2026
AVAILABLE BEFORE 8/7/2026

Principal Investigator – Clinical Research (Endocrinology Focus)

Location: 100% On-site (QPS office/lab)


QPS is seeking an experienced Principal Investigator (PI) to lead clinical trials and provide senior oversight across our research portfolio. In this role, you’ll manage your own studies while supporting PRN and Contract PIs, ensuring trials run smoothly, subjects are safe, and data integrity is maintained.


Why This Role Matters:

You’ll stay closely involved in study conduct while influencing overall trial quality, mentoring colleagues, and shaping how research is executed. Endocrinology or metabolic expertise is particularly helpful - especially in areas like diabetes, GLP-1, obesity, or thyroid—offering the chance to apply your specialty in a dynamic clinical research setting.


What You’ll Do:

  • Lead and oversee clinical trials in compliance with ICH-GCP and protocol requirements
  • Serve as a clinical resource and back-up for PRN and Contract PIs
  • Ensure subject safety, informed consent, and regulatory compliance
  • Mentor and guide research staff and Sub-Investigators
  • Interface with sponsors, IRBs, monitors, and auditors


What we seek:

  • MD or DO (Board Certified)
  • Strong working knowledge of ICH-GCP and clinical research regulations
  • Experience leading clinical studies as a PI or Sub-Investigator
  • Endocrinology expertise or therapeutic-area experience helpful
  • Candidates with a strong endocrinology background will be considered even without prior CRO experience
  • Comfortable operating with a high degree of autonomy while collaborating across teams
  • Excellent written and verbal communication skills
  • Comfortable working with MS Office and standard clinical research systems
  • Ability to work a flexible schedule, including occasional nights, weekends, and holidays


Join QPS and make a direct impact on study quality, while mentoring the next generation of investigators in a collaborative environment.


QPS, LLC is an Equal Employment Opportunity/Affirmative Action Employer. Job applicants and present employees are evaluated solely on ability, experience, and the requirements of the job. Learn more at https://www.qps.com/careers/


Salary : $175,000 - $225,000

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