What are the responsibilities and job description for the Sr Associate Scientist position at Proclinical Staffing?
Sr Associate Scientist - Contract - Boston, MA
Drive the chemistry behind next‑generation immuno‑oncology therapies.
Proclinical is seeking a Sr Associate Scientist to join a dynamic team in Boston, MA. The position offers an exciting opportunity to contribute to cutting-edge work in the immuno-oncology and pharmaceutical space.
Primary Responsibilities:
The successful candidate will focus on hands-on laboratory support and process development for the chemical synthesis and downstream processing of oligonucleotide-based drug substances.
Skills & Requirements:
- A degree in Chemistry or a related field with relevant laboratory experience, preferably in an industrial setting.
- Basic understanding of analytical techniques such as pH, osmolality, conductivity measurement, HPLC, and LC-MS.
- Hands-on experience with oligonucleotide manufacturing processes, including phosphoramidite chemistry, chromatography, and ultrafiltration, is a plus.
- Strong commitment to maintaining high laboratory and scientific standards.
- Excellent communication skills and the ability to work collaboratively in a fast-paced, team-oriented environment.
- Proactive and responsible approach to work, with the ability to meet aggressive timelines.
The Sr Associate Scientist's responsibilities will be:
- Perform chemical synthesis of oligonucleotides at scales up to 11 mmol.
- Conduct downstream processing of oligonucleotides, including preparative HPLC, ultrafiltration, annealing, concentration, and lyophilization.
- Carry out in-process analytical testing using techniques such as AX-HPLC, IPRP-HPLC, LC-MS, and UV-vis.
- Provide technical support for optimizing contract manufacturing processes.
- Maintain a safe, clean, and organized laboratory environment, assisting with routine lab and equipment maintenance.
- Ensure accurate record-keeping and adherence to excellent laboratory documentation practices.
If you are having difficulty in applying or if you have any questions, please contact Mike Raletz at m.raletz@proclinical.com.
If you are interested in applying to this exciting opportunity, then please click 'Apply' or to speak to one of our specialists please request a call back at the top of this page.
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