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Chief Of Staff / Operations Lead

Prime Intellect
San Francisco, CA Full Time
POSTED ON 1/17/2026 CLOSED ON 2/16/2026

What are the responsibilities and job description for the Chief Of Staff / Operations Lead position at Prime Intellect?

About Prime Intellect

Prime Intellect is building the infrastructure for decentralized AI. By enabling global collaboration in compute, code, and capital, we’re accelerating the development of open-access AI models with a bold vision: AGI that benefits everyone.

Role: Chief of Staff / Operations Lead

We’re hiring a Chief of Staff / Operations Lead to partner with our CEO, CTO, and COO on building the foundations of Prime Intellect. This is a strategic operations role: you’ll design and run the systems that keep the company moving at speed, while also leading key initiatives across hiring, culture, and external partnerships.

Your scope will range from managing core operations (housing, events, logistics) to shaping workflows, driving team growth, and strengthening relationships with investors and collaborators. At its core, the role is about creating the structure and environment that allow Prime Intellect to scale — ensuring leadership and the broader team can stay focused on advancing decentralized AI.

Operations & Execution

  • Oversee day-to-day logistics including housing, moves, events, and vendor management.
  • Coordinate team gatherings such as off-sites, hackathons, and community dinners.
  • Anticipate and resolve operational challenges quickly and effectively.

Team Building & Support

  • Lead hiring processes across operations, business, and legal functions.
  • Support and mentor team members to foster a collaborative, results-driven culture.
  • Identify resourcing gaps and ensure teams have the tools they need to succeed.

Operational Excellence

  • Design and refine workflows that improve productivity and scalability.
  • Implement systems for continuous improvement across the organization.
  • Develop and track metrics to measure performance and identify improvements.

Stakeholder Engagement

  • Build strong relationships with investors, partners, and collaborators.
  • Serve as a point of contact for external inquiries and partnerships.
  • Support leadership in fundraising prep and investor communications.

Who You Are

  • Proven experience as Chief of Staff, operations leader, or similar role in a fast-paced, high-growth tech environment.
  • Strong organizational skills and ability to juggle shifting priorities.
  • Comfortable working side-by-side with founders and senior leadership.
  • People-oriented and resourceful, with a bias for solving problems quickly Requirements
  • Strong track record of aligning teams to execute ambitious goals at scale.
  • Experience with hiring, team development, and fostering high-performing teams.
  • Business acumen with experience in financial management and fundraising.
  • Outstanding communication and interpersonal skills, including executive-level reporting.

What we offer

  • Competitive compensation, including generous equity compensation.
  • San Francisco HQ incl lunch and other benefits.
  • Visa sponsorship and relocation support for international candidates.
  • Quarterly team off-sites, hackathons, and growth opportunities.
  • A chance to shape the future of decentralized AI alongside a passionate, mission-driven team.

We recently raised $15mm in funding (total of $20mm raised) led by Founders Fund, with participation from Menlo Ventures and prominent angels including Andrej Karpathy (Eureka AI, Tesla, OpenAI), Tri Dao (Chief Scientific Officer of Together AI), Dylan Patel (SemiAnalysis), Clem Delangue (Huggingface), Emad Mostaque (Stability AI) and many others.

Salary.com Estimation for Chief Of Staff / Operations Lead in San Francisco, CA
$199,186 to $258,778
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