What are the responsibilities and job description for the Scientist II position at Orion Group?
Scientist II
$59 - $62/hr with medical benefits available at a cost
6 month initial contract with possibility of extension
Onsite in South San Francisco
Standard first shift M-F
Orion Project Services and our largest US client are teaming up for an exciting contract opportunity for Pharmaceutical Scientists in South San Francisco!! We are seeking candidates with experience in the development, optimization and implementation of novel and routine LC/MS-based bioanalytical methods to support in vivo PK, TK, and PK/PD studies as well as in vitro stability characterization of therapeutic proteins, peptides, and oligonucleotides.
Don’t pass on this amazing chance to join a market leading pharmaceutical company!!!!!!
Job Description:
The Quantitative, Translational ADME Sciences (QTAS) department is seeking a highly motivated scientist to join the Biologics bioanalysis, characterization, and proteomics group. The successful candidate will be experienced in the development, optimization and implementation of novel and routine LC/MS-based bioanalytical methods to support in vivo PK, TK, and PK/PD studies as well as in vitro stability characterization of therapeutic proteins, peptides, and oligonucleotides. The candidate will be responsible for sample preparation, method development, bioanalytical assay operations, data analysis, report generation, and data presentation.
Key tasks and responsibilities:
Qualifications:
As an international workforce business, we are committed to sourcing personnel that reflects the diversity and values of our client base but also that of Orion Group. We welcome the wide range of experiences and viewpoints that potential workers bring to our business and our clients, including those based on nationality, gender, culture, educational and professional backgrounds, race, ethnicity, sexual orientation, gender identity and expression, disability, and age differences, job classification and religion. In our inclusive workplace, regardless of your employment status as staff or contract, everyone is assured the right of equitable, fair and respectful treatment.
$59 - $62/hr with medical benefits available at a cost
6 month initial contract with possibility of extension
Onsite in South San Francisco
Standard first shift M-F
Orion Project Services and our largest US client are teaming up for an exciting contract opportunity for Pharmaceutical Scientists in South San Francisco!! We are seeking candidates with experience in the development, optimization and implementation of novel and routine LC/MS-based bioanalytical methods to support in vivo PK, TK, and PK/PD studies as well as in vitro stability characterization of therapeutic proteins, peptides, and oligonucleotides.
Don’t pass on this amazing chance to join a market leading pharmaceutical company!!!!!!
Job Description:
The Quantitative, Translational ADME Sciences (QTAS) department is seeking a highly motivated scientist to join the Biologics bioanalysis, characterization, and proteomics group. The successful candidate will be experienced in the development, optimization and implementation of novel and routine LC/MS-based bioanalytical methods to support in vivo PK, TK, and PK/PD studies as well as in vitro stability characterization of therapeutic proteins, peptides, and oligonucleotides. The candidate will be responsible for sample preparation, method development, bioanalytical assay operations, data analysis, report generation, and data presentation.
Key tasks and responsibilities:
- The main function of this position is to develop and implement LC/MS (liquid chromatography/mass spectrometry)-based bioanalysis and in vitro characterization assays for novel biologics entities.
- Operate and maintain LC/MS instruments to generate high-quality experimental data.
- Perform affinity purification of therapeutic proteins (including but not limited to monoclonal and bispecific antibodies, antibody drug conjugates, antibody-siRNA conjugates, and fusion proteins) from biological matrices.
- Analyze data and maintain detailed, accurate and comprehensive study documentation in electronic laboratory notebooks.
- Facilitate assay optimization and implementation to ensure laboratory capacity and data quality.
- Communicate data interpretation internally and externally.
Qualifications:
- Degree in chemistry, pharmacology or other related fields. BS with 5 years or MS with 2 years in a pharmaceutical industry setting with a focus on mass spectrometry.
- Experience on routine LC/MS-based bioanalysis to support in vivo PK, TK, and PK/PD studies
- Highly motivated, self-driven and results-oriented with excellent communication and presentation skills; capable of working both as a team player and individual contributor.
- Prior industry experience in drug discovery/development is preferred. In-depth understanding of PK, TK and PK/PD studies and corresponding bioanalytical assays as well as in vitro characterization assays is highly desired.
- Hands-on experience with QQQ (SCIEX), qTOF (Agilent, Bruker, SCIEX) and/or Orbitrap (Thermo) mass spectrometers is highly desired.
- Hands-on experience with automated liquid handling systems is highly desired.
- Hands-on experience with oligonucleotide analysis is highly desired.
As an international workforce business, we are committed to sourcing personnel that reflects the diversity and values of our client base but also that of Orion Group. We welcome the wide range of experiences and viewpoints that potential workers bring to our business and our clients, including those based on nationality, gender, culture, educational and professional backgrounds, race, ethnicity, sexual orientation, gender identity and expression, disability, and age differences, job classification and religion. In our inclusive workplace, regardless of your employment status as staff or contract, everyone is assured the right of equitable, fair and respectful treatment.
Salary : $59 - $62
