What are the responsibilities and job description for the Senior Scientist position at NodoN Inc?
Location: NodoN, Inc, Austin, Texas
We are seeking a Principal Scientist to join our dedicated and innovative research team at Nodon Bio. This role is pivotal in developing a best-in-class technology platform for producing novel protein therapeutics. The successful candidate will be a scientific leader, driving key projects from concept to execution in the lab, with a direct and long-term impact on the company's strategic direction.
Desired Qualifications
- Advanced degree in chemistry/bioengineering/biochemistry/molecular biology/genomics preferred. PhD with 0-3 years of experience post doctorate experience, MS with 2-5 years work experience, or BA/BS with 4-7 years work experience desired.
- Experience with high-throughput mammalian genome modification is a plus
- Software Proficiency: SnapGene, Excel, PowerPoint, R/Python.
- Excellent oral communication and organizational skills
- Ability to distill complex scientific information into practical actions and communicate effectively to a general audience.
Core Technical Skills & Expertise
Molecular and Cell Biology:
- Advanced primer design, PCR, and cloning.
- Gene expression cassette design, construct assembly, manufacturing, purification, and quality control (QC).
- High-throughput genome engineering using gene editing technologies.
- Expertise in mammalian cell culture, particularly with CHO and HEK cell lines.
- Experience with single-cell cloning, expansion, and QC.
- Experience implementing whole genome sequencing, both in wetlab and informatics analysis
- Cell-based activity assays, including fluorescence microscopy, and luciferase assays.
Genomic Analysis:
- NGS and long-read sequencing library preparation.
- Sequencing QC and advanced bioinformatics data analysis.