Executive Director, Procurement

Brief Description

Company Background

The mission of Neurogene is to treat devastating neurological diseases to improve the lives of patients and families impacted by these rare diseases. Neurogene is developing novel approaches and treatments to address the limitations of conventional gene therapy in central nervous system disorders. This includes selecting a delivery approach to maximize distribution to target tissues and designing products to maximize potency and purity for an optimized efficacy and safety profile. The Company’s novel and proprietary EXACT transgene regulation platform technology allows for the delivery of therapeutic levels while limiting transgene toxicity associated with conventional gene therapy. Neurogene has constructed a state-of-the-art gene therapy manufacturing facility in Houston, Texas. CGMP production of NGN-401 was conducted in this facility and will support pivotal clinical development activities. This transformative work is driven by our highly collaborative people who come together each day to bring us closer to achieving our mission. As an employee of Neurogene, you will be part of building a culture that honors patient and caregiver mindsets and nurtures innovation, creative problem solving and a strong sense of purpose.

Position Overview - New York Or Remote

We are seeking a highly strategic and execution-oriented Executive Director of Strategic Sourcing & Procurement to build and lead a best-in-class procurement function within a fast-growing life sciences organization. This leader will design and scale procurement as a value-creating business function that delivers cost optimization, operational efficiency, transparency, risk management, and strategic vendor partnerships across the enterprise.

This role will be responsible for end-to-end sourcing, procurement, contract negotiation, vendor management, process design, spend governance, and procurement analytics—serving as a strategic partner to Finance, Legal, Operations, R&D, Clinical, CMC, and Commercial teams. The ideal candidate combines deep life sciences domain expertise with strong commercial acumen, financial rigor, operational discipline, and systems thinking.

Requirements

Accountabilities and Responsibilities

Strategic Sourcing & Vendor Management

• Build and execute enterprise-wide sourcing strategies across key spend categories (e.g., CROs, CDMOs, clinical services, IT/SaaS, professional services, lab suppliers, manufacturing, facilities, and corporate services)
• Develop category strategies, preferred vendor programs, and competitive sourcing frameworks
• Lead RFPs, RFQs, and vendor selection processes for high-value and strategic initiatives
• Establish long-term strategic supplier partnerships while maintaining competitive tension
• Implement vendor performance management frameworks and scorecards
  
  

Contracting & Commercial Negotiation

• Lead complex commercial negotiations, including pricing models, rate cards, MSAs, SOWs, and multi-year strategic agreements
• Partner with Legal to standardize contracting frameworks, templates, and risk controls
• Drive contract value protection through pricing controls, audit rights, change order governance, and renewal management
• Implement contract lifecycle management and renewal optimization processes
  
  

Process Design & Procurement Operations

• Design scalable procurement processes across intake, sourcing, approvals, purchasing, contracting, and payment
• Build governance models, delegation of authority frameworks, and spend controls
• Develop standardized procurement workflows that balance control with operational speed
• Implement best-in-class P2P and sourcing systems and tools
• Drive continuous process improvement through process mapping, automation, and optimization
  
  

Financial Integration & Business Partnership

• Integrate procurement with financial planning, budgeting, forecasting, and capital allocation processes
• Support business development and strategic initiatives through commercial due diligence, cost modeling, and vendor strategy
• Partner with Finance on cash management, burn rate optimization, and runway extension
• Deliver cost savings, cost avoidance, and value realization programs
• Build strong cross-functional partnerships with R&D, Clinical, CMC, Operations, IT, and Corporate functions
  
  

Analytics, Reporting & Transparency

• Build procurement analytics and reporting capabilities including spend visibility, contract coverage, vendor concentration, budget vs. actuals, and risk exposure
• Develop executive dashboards and KPI frameworks
• Enable data-driven decision-making across sourcing and spend governance
• Establish spend classification taxonomies and data standards
  
  

Risk Management & Compliance

• Identify and mitigate vendor, supply chain, financial, regulatory, and operational risks
• Implement procurement controls, audit trails, and compliance frameworks
• Support SOX-ready and audit-ready procurement operations
• Manage single-source risk, supplier dependency, and supply continuity strategies
  
  

Minimum Requirements

Education

• Bachelor’s degree required in business, supply chain, procurement, engineering, finance, life sciences, or a related field.
• MBA or other advanced degree preferred.
  
  

Experience

• 13 years of progressive experience in strategic sourcing, procurement, and supply chain leadership
• Deep experience in life sciences, biotech, pharma, or medical technology
• Proven Expertise in: Strategic sourcing, contract negotiation, commercial deal structuring, vendor management, process design and optimization, project management, procurement systems implementation, and spend governance
• Strong financial acumen, including forecasting, budgeting, cost modeling, and financial analysis
• Demonstrated ability to build functions from the ground up
• Track record of delivering measurable cost savings and operational improvements
• Executive-level communication and stakeholder management skills
• Preferred: Experience in high-growth environments; experience supporting clinical-stage and commercial-stage operations; background working cross-functionally with Legal, Finance, R&D, Clinical, and Operations; experience implementing procurement and contract lifecycle management systems
  
  

Success Metrics

• Spend under management %
• Contract compliance %
• Cost savings and cost avoidance
• Cycle time reduction
• Vendor performance metrics
• Budget adherence
• Procurement adoption rates
• Risk exposure reduction
• Transparency and reporting quality
  
  

Licenses or Certifications

• N/A
  
  

Knowledge, Skills And Attributes

• Strategic thinking & systems design
• Commercial negotiation & deal structuring
• Financial modeling & forecasting
• Process engineering
• Data analytics & reporting
• Change management
• Cross-functional leadership
• Risk management
• Vendor relationship management
• Operational execution
• Highly analytical and structured
• Commercially aggressive but relationship-driven
• Data-driven and financially disciplined
• Operationally pragmatic
• Comfortable building from zero
• Trusted partner to executive leadership
• Able to operate at both strategic and execution levels
• Comfortable in ambiguity and high-growth environments
• Continuous strong focus on meeting or exceeding expectations in executing deliverables, performance and results.
• Ability to track and measure performance against defined metrics.
• Self-starter with high degree of energy, independence, initiative, and self-motivation, as illustrated by the ability to instill a sense of pace and urgency into the team.
• Someone who moves fast and decisively in a balanced manner, with a passion for the growing company.
• Passionate, collaborative, creative, willing to take prudent risks, and motivated by the creation of a company focused on transformative treatments for patients and their families.
  
  

This job description has been developed based upon the expected and current duties, responsibilities and requirements for the position. Because job requirements evolve with the changing needs of Neurogene’s business, this description is subject to change and may be modified at any time, whether formally or informally.