Senior Researcher

Job Title: Research Associate III

Location: Framingham, MA

Duration: 12 months with possible extension

Description:

We are seeking a highly motivated candidate for an open position within the Cell Line Development (CLD) team creating recombinant CHO cell lines to support research and preclinical development programs within. The person in this role will work in a high-performing, fast-paced collaborative environment supporting end-to-end development of recombinant CHO cell lines and platform optimization for our future CHO expression platforms. Work will directly support the advancement of projects in Sanofi’s biologics pipeline. Key responsibilities will include sterile cell culture techniques with suspension cultures, pool and clone generation, data assessment and communication, among other things.

Position Overview/Key Responsibilities:

• Assist in generation of engineered mammalian cell lines (transfection pools, clones) expressing candidate biotherapeutics

• Assist in several studies simultaneously to optimize cell line generation processes.

• Perform mammalian cell culture techniques: sterile technique, cell counting, passaging, cryopreservation, etc.

• Perform basic molecular biology techniques: DNA plasmid preparation, PCR, restriction enzyme digestion, etc.

• Self-motivated with excellent attention to detail and superb organizational skills

• Proven ability to work in a highly collaborative environment and communicate transversally

• Flexibility, adjusting to a fast-paced, goal-oriented environment and willingness to expand and broaden one’s skillset

• Prepare reports, presentations, and data sets to effectively communicate results, progress and plans

• Strong technical background

• Experience with data management, consolidation, and presentation

• Contribute to lab organization, reagent tracking and other tasks as determined appropriate

• Compliance with all applicable regulations, ensure that work performed is conducted in a safe and compliant manner, maintenance of proper records in accordance with SOPs and policies

• Presentation of data at lab meetings

Basic Qualifications:

• Bachelor’s Degree / Master's Degree in Biology, Cellular Biology, Molecular Biology or equivalent (preferably in Cellular Biology research).

Bachelors Degree with 8-10 years experience, Masters with 4-5 years exp, or PhD with 2-3 years exp. Needs person to be able to hit the ground running. Will be dividing time in lab and meetings. MUST HAVE: Mammalian CHO Cell Culture experience, Molecular Biology (years of experience based on education level listed above).

Preferred Qualifications:

• Experience in suspension culture of CHO cell lines in a pharmaceutical or biotechnology setting

• Knowledge of techniques

EEO:

“Mindlance is an Equal Opportunity Employer and does not discriminate in employment on the basis of – Minority/Gender/Disability/Religion/LGBTQI/Age/Veterans.”