Clinical Principal Investigator

We are seeking a full-time Principal Investigator. The Clinical Principal Investigator (PI) is a physician-scientist responsible for the overall preparation, conduct, and management of sponsored projects, ensuring compliance with all regulatory requirements and institutional policies. This role oversees the development, implementation, and execution of clinical trial protocols, contributes to the analysis and interpretation of clinical data, and ensures the integrity and quality of research outcomes. The PI will maintain effective communication and alignment with study sponsors, regulatory bodies, and internal stakeholders, while providing strategic leadership to research staff and fostering a culture of excellence, compliance, and ethical research conduct.

This role is based on-site in Bakersfield, CA.

Essential Responsibilities

• Manage clinical trials by providing medical direction and comprehensive medical reviews of protocols in conformance with the investigational plan and Good Clinical Practice.
• Lead and manage a matrixed team responsible for the conduct of Phase II/III oncology trials.
• Ensure the safety and well-being of all participants at the trial site.
• Ensure data collected at the study site is credible, accurate, and complete.
• Protect the rights, integrity, and confidentiality of all trial participants.
• Provide expert guidance and support to clinical operations research staff and sponsor partners.
• Lead continuous quality improvement efforts for clinical research services, integrating best practices and fostering a culture of research excellence.
• Develop and implement strategies to enhance patient recruitment and retention in clinical trials.

Required Education & Experience

• Doctor of Medicine (M.D.) or equivalent degree required; Ph.D. strongly preferred.
• Board certification in Hematology and/or Medical Oncology.
• Clinical trials experience with a strong interest in drug development.
• Ability to critically analyze clinical scientific data and medical literature.
• Working knowledge of GCP principles, safety and adverse event reporting, FDA regulations, and biomedical research ethics.
• Passion for providing excellent clinical care within a collaborative, team-oriented environment.
• Prior experience with industry-sponsored clinical trials.
• Translational research experience, including familiarity with pharmacokinetics and pharmacodynamics.

Best-in-Class Benefits & Perks

• Comprehensive health coverage, including medical, dental, and vision insurance options.
• Robust retirement planning with a 401(k) plan and employer matching.
• Commitment to well-being and work-life balance, including paid time off and flexible scheduling.
• A supportive environment where employees are encouraged to learn, grow, and advance professionally.
• A collaborative and creative culture that values input into processes, decisions, and organizational planning.
• Deep roots in community oncology, providing access to specialized late-phase clinical trials of novel anti-cancer agents.
• A strong commitment to accelerating the transition from clinical trials to effective treatments, delivering hope to patients and families.

Changing the Future of Cancer Treatment

Join a mission-driven organization dedicated to advancing cancer care through rigorous, patient-centered clinical research. By contributing your expertise and leadership, you will play a vital role in expanding access to innovative therapies and improving outcomes for patients both locally and globally.

This is a privately owned, community-based cancer clinic with a solid referral base, diverse payer mix, and a broad patient population supported by a compassionate and experienced staff. The team is deeply committed to patient well-being, emphasizing hope, comfort, and compassion. The ideal candidate will share this mission and a dedication to delivering high-quality, innovative oncology care.

The organization maintains an extensive network of surgeons, radiation oncologists, pathologists, imaging centers, hospitals, and laboratories to provide comprehensive patient support. Affiliations include nearby acute care hospitals located approximately 1.5 miles from the infusion center.

Through an active clinical trials program, patients are offered access to novel cancer therapies. Clinical facilities include 16 infusion chairs, an in-house chemotherapy laboratory, on-site genetic testing, six exam rooms, and three private oncologist offices.

The organization strongly supports oncologists’ career goals and professional development, whether focused on clinical trial research, medical education, or clinical practice.