What are the responsibilities and job description for the Senior Clinical Pharmacologist (Sr. Scientist) position at Melinta Therapeutics LLC?
Why CorMedix Therapeutics?
If you are interested in joining an entrepreneurial team, focused on bringing life-saving therapies to market for critical unmet medical needs, consider applying for a role at CorMedix Therapeutics. The culture at CorMedix Therapeutics is patient-centered where we feel a sense of urgency to solve some of the most pressing issues in hospital-based healthcare. CorMedix Therapeutic’s greatest asset is our people. We have a deeply experienced team and continue to bring on some of the brightest talent that can problem solve and execute with high precision. We are passionate about the work we do and how we do it. We believe in building highly engaged teams that exude integrity, open communication, and innovation. We believe in fostering each employee to reach their highest potential by offering an inclusive environment, opportunities to challenge yourself and grow, and a community of purpose. We expect that everyone here brings their best selves to work and together, our singular efforts culminate into profound and meaningful breakthroughs.
Company Description:
CorMedix Therapeutics is a biopharmaceutical company focused on developing and commercializing therapeutic products for the prevention and treatment of life-threatening conditions and diseases. CorMedix is commercializing DefenCath® (taurolidine and heparin) for the prevention of catheter-related bloodstream infections in adult patients undergoing hemodialysis via a central venous catheter. Following its August 2025 acquisition of Melinta Therapeutics LLC, CorMedix is also commercializing a portfolio of anti-infective products, including MINOCIN® (minocycline), REZZAYO® (rezafungin), VABOMERE® (meropenem and vaborbactam), ORBACTIV™ (oritavancin), BAXDELA® (delafloxacin), and KIMYRSA® (oritavancin), as well as TOPROL-XL® (metoprolol succinate). CorMedix Therapeutics has ongoing clinical studies for DefenCath in Total Parenteral Nutrition and Pediatric patient populations and also intends to develop DefenCath as a catheter lock solution for use in other patient populations. REZZAYO is currently approved for the treatment of candidemia and invasive candidiasis in adults, with an ongoing Phase III study for the prophylaxis of invasive fungal disease (IFD) in adult patients undergoing allogeneic BMT. Topline results of the Phase III study for REZZAYO are expected in Q2 2026. For more information visit: www.cormedix.com or www.melinta.com.
Position:
We are seeking a highly motivated Senior Clinical Pharmacologist (Sr. Scientist) to support clinical pharmacology activities with a focus on hands-on technical execution. This is a non-strategic, execution-focused role, ideal for an early-career scientist eager to apply their training in a real-world drug development setting. The successful candidate will work closely with internal leads to deliver PK analyses, data interpretation, and study support, collaborating with cross-functional teams and external partners, including pharmacometrics and CRO groups. You will contribute to the design and interpretation of clinical pharmacology studies, develop a strong understanding of how PK parameters are generated and applied, and help ensure work aligns with regulatory expectations (FDA, EMA, ICH). This position is best suited for someone with a strong foundation in pharmacokinetics and clinical pharmacology who enjoys hands-on analytical work, cross-functional collaboration, and working with external experts.
Key Responsibilities
- Perform, review, and interpret pharmacokinetic (PK) analyses, including non‑compartmental and model‑informed approaches
- Support the design, execution, and analysis of clinical pharmacology studies in humans
- Contribute to the development, refinement of study protocols,with emphasis on PK-related sections
- Prepare and review clinical pharmacology content for key clinical and regulatory documents, including clinical study reports, regulatory submission modules, and briefing materials (e.g., FDA briefing books)
- Collaborate with cross‑functional teams to address PK‑related questions and support timely delivery of clinical pharmacology outputs
- Interface with external CROs and pharmacometrics partners, managing contracts, reviewing outputs and ensuring quality of deliverables
- Interpret clinical pharmacology data to inform program‑level and dose‑selection decisions
- Apply relevant regulatory guidance to ensure analyses and reporting are compliant, consistent, and scientifically rigorous
Experience
- 1–2 years of relevant industry experience (postdoctoral experience may be considered)
- Experience performing and interpreting noncompartmental pharmacokinetic (NCA) analyses
- Experience authoring PK study reports
- Experience developing, evaluating, and interpreting population pharmacokinetic (PopPK)models, with an understanding of FDAPopPKguidance and regulatory standards
- Experience supporting clinical study execution
- Experience collaborating with cross-functional teams (Clinical Ops, Regulatory, CMC) and/or external partners/CROs
Preferred Experience
- Experience in antibiotic development
- Proficiency in data analysis and population PK modeling using tools such as R, NONMEM,WinNonlin,orrelated platforms
Education
- PhD or PharmD with focus in Pharmacokinetics, Pharmacology, Pharmaceutical Sciences, or a closely related field
- Strong foundation in clinical pharmacology principles, PK, and study design
Work Location
- This is a fully remote role with flexibility to work from home.
- Occasional in-person collaboration may be required at our headquarters in Parsippany, New Jersey.
Salary : $162,000 - $175,000