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Director / Sr Director Clinical Pharmacology

Meet Life Sciences
South San Francisco, CA Full Time
POSTED ON 4/24/2026
AVAILABLE BEFORE 5/23/2026

Director / Sr Director Clinical Pharmacology & DMPK

South San Francisco - 3 days in office/week (Tu/We/Th)


Seeking a (Sr) Director of Clinical Pharmacology & DMPK for a Biotech focused on small-molecule programs in immune-mediated diseases. This role partners cross-functionally and reports to the Head of Clinical Pharmacology & DMPK.


Responsibilities:

  • Lead clinical pharmacology strategy, dose selection, and PK/PD, biomarker planning across programs
  • Conduct and interpret PK, PK/PD, exposure–response, and simulation analyses (e.g., NONMEM, WinNonlin, R, Python, Simcyp)
  • Integrate translational and nonclinical data for FIH dose projections and DDI assessments
  • Oversee bioanalytical CROs and ensure high-quality, compliant data
  • Support protocol design, sample management, and regulatory documents (INDs, NDAs, etc.)
  • Collaborate across Clinical Development, Biostats/Data Science, Nonclinical, and Program Management


Qualifications:

  • PhD, PharmD, or equivalent in a relevant field
  • 8 years of industry experience in Clinical Pharmacology, DMPK, or related area
  • Strong expertise in PK/PD, DMPK, and translational science
  • Experience with modeling/simulation tools (e.g., NONMEM, WinNonlin, Simcyp, R, Python)
  • Strong communication and ability to work in a fast-paced environment

Salary : $200,000 - $270,000

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