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Purification Scientist

Managed Staffing
Boston, MA Contractor
POSTED ON 12/15/2025
AVAILABLE BEFORE 2/14/2026
Biologist - Purification ScientistClient: Eli Lilly and CompanyLocation: Boston, MA (Onsite)Schedule: Monday–Friday | 8:00 AM–5:00 PM (40 hrs/weekPosition SummarySeeking an early-career Biologist / Purification Scientist to join the Downstream Process Development team in Boston, MA. This role will support purification and characterization of viral vectors, biologics, or recombinant proteins for process development and manufacturing activities. The ideal candidate has hands-on laboratory experience with chromatography-based purification techniques and strong documentation and collaboration skills.Key ResponsibilitiesExecute purification processes including affinity chromatography (e.g., AVB, CaptureSelect), ion-exchange chromatography (AEX, CEX), and polishing stepsOperate AKTA systems (Avant, Pure, Pilot) for small- to large-scale purification runsPerform tangential flow filtration (TFF) for buffer exchange and product concentrationPrepare buffers and manage chromatography columns and consumablesSupport experimental design, data collection, and detailed documentation in accordance with GMP/GLP practicesAssist with troubleshooting and optimization of purification processesAnalyze samples using standard analytical techniques (e.g., UV, SDS-PAGE, ELISA, ddPCR, HPLC)Collaborate with upstream process, analytical, and manufacturing teamsMaintain laboratory equipment and ensure compliance with safety and quality standardsRequired QualificationsMaster’s degree in Biochemistry, Biotechnology, Chemical Engineering, or a related scientific disciplineMinimum 2 years of hands-on purification experience in an academic or industry laboratoryPractical experience with ion-exchange and affinity chromatographyExperience with buffer preparation and basic analytical characterization methodsStrong attention to detail with excellent documentation practicesAbility to manage multiple tasks and meet project timelinesEffective written and verbal communication skillsPreferred QualificationsExperience with AAV or other viral vector purificationHands-on experience with AKTA systems and Unicorn softwareExposure to downstream process development or biomanufacturing environments

Salary : $44 - $46

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