What are the responsibilities and job description for the Medical/Sr. Med Director (MD) – Early Clinical Development position at LTZ Therapeutics?
About Us
LTZ Therapeutics is a clinical-stage, immunotherapy-focused biotechnology company pursuing the development of novel therapies, with the company's Universal Myeloid Cell Engager (U-MCETM) Platform, to improve clinical outcomes in patients with oncology and autoimmune diseases. With main operations in Redwood City, California and Shenzhen China, LTZ is dedicated to developing myeloid engager immunotherapies for broad disease indications. For more information, please visit https://www.ltztherapeutics.com/.
Role Overview
We are seeking a highly motivated, execution-focused Medical Director (MD) to lead and support early clinical development efforts, from IND submission activities through initiation and execution of clinical trials.
This is a hands on role ideal for a results-driven person who thrives in a startup environment; someone who takes ownership, drives timelines, and works cross-functionally to get things done. You will play a critical role in bridging preclinical and clinical development while ensuring high-quality, compliant execution.
This position will report directly to the Chief Medical Officer (CMO).
Key Responsibilities
Clinical Development & Strategy
- Leads the design and execution of oncology clinical trials (e.g., dose escalation, first-in-human studies).
- Leads the clinical study team in protocol development, protocol monitoring, data review, study report, and other clinical and regulatory documents.
- Leads the clinical development product team to facilitate clinical development goals and achievement of quality study metrics.
- Contributes to the organization, preparation, and execution of investigator and scientific advisory board meetings in collaboration with project teams.
- Maintain current information regarding industry regulations, guidelines, and scientific advances for oncology immunotherapies.
- Fosters relationships and represent LTZ with external partners such as clinical investigators, clinicians, KOL, and scientist in support of business development.
- Review safety data, adverse events, efficacy and emerging signals; escalate issues as needed
- Participate in safety review committees and data monitoring activities.
- Able to effectively work across multiple projects and teams.
Qualifications
Required
- Medical oncologist (MD or equivalent medical degree) with 5 years of clinical research experience.
- Experience in analysis and interpretation of clinical data (safety and efficacy) and a working knowledge of requirements for clinical studies (biostatistics, biomarker, GCP, and regulatory, etc.).
- Intellectual curiosity, flexibility, and persistence.
- Strong understanding of solid tumor clinical development.
- Able to make timely, independent, and appropriate decisions.
- Able to multitask, work in a fast-paced environment, and lead multiple projects.
- Ability to maintain flexibility and re-prioritize based on changing demands.
- Strong written and verbal communication skills and ability to collaborate with all levels of an organization and vendors.
- Ability to travel.
- Experience working in small biotech or lean teams.
Experience Level: ~5 years post-residency/clinical training in oncology; Ideal candidate will have 2 years of biotech or pharma experience with clinical trial design and execution of early clinical programs in oncology.
Why Join Us
- Opportunity to shape early clinical development in high-impact oncology programs
- High visibility and ownership in a growing biotech company
- Collaborative, mission-driven team environment
- Competitive compensation and equity package
If you’re excited to roll up your sleeves and help bring novel cancer therapies from bench to bedside, we’d love to hear from you.