Demo

Associate Director Clinical Operations

Latitude Inc
Germantown, MD Full Time
POSTED ON 12/31/2025
AVAILABLE BEFORE 1/31/2026

Associate Director of Clinical Operations | Hybrid


A clinical-stage biotherapeutics organization is seeking an Associate Director of Clinical Operations to support its growing portfolio of innovative clinical programs. This position offers a hybrid work model, the opportunity to work in a dynamic and collaborative environment, and involvement in cutting-edge immunology and autoimmune research.


Key Responsibilities

• Manage and oversee all operational aspects of assigned clinical studies in alignment with internal SOPs, ICH GCP, applicable laws, and regulatory guidelines.

• Lead and coordinate cross-functional study teams.

• Ensure study deliverables are met with high quality and within agreed timelines.

• Prepare and coordinate clinical study documentation, including protocols, IBs, DSURs, ICFs, and CSRs.

• Select and oversee CROs, contract monitors, and external vendors.

• Participate in clinical site selection with internal teams and CRO partners.

• Conduct periodic co-monitoring to ensure high-quality site monitoring and data integrity.

• Set up and manage clinical contracts, including Clinical Site Agreements.

• Coordinate IRB/IEC submissions and support regulatory submission packages.

• Develop and manage study budgets, forecasting, and accruals.

• Maintain thorough documentation of study decisions, actions, and risk assessments.

• Actively manage clinical supply needs in partnership with third-party distribution specialists.

• Oversee Sponsor Oversight Files and/or TMF creation and maintenance to ensure inspection readiness.

• Continuously develop therapeutic area knowledge relevant to assigned studies.


Essential Qualifications

• BSc or equivalent degree.

• Clinical study management experience within pharma, biotech, or CRO settings.

• Proven vendor oversight experience (CROs, central labs, imaging vendors, etc.).

• Strong written, verbal, and presentation skills.

• Excellent organizational, interpersonal, and time-management capabilities.

• Ability to manage multiple priorities across programs.

• Strong working knowledge of GCP and current clinical trial regulations.

• Thorough understanding of the clinical development process from early-phase through regulatory submission.

• Ability to travel domestically and internationally as needed.

• Comfortable working in a dynamic small-team environment.


Desired Skills

• Experience in early-phase (I–II) clinical studies.

• GMO study experience.

• Background as a CRA or clinical monitor.

• Familiarity with EDC, eTMF, and CTMS systems.

• Experience in autoimmune diseases and immunology.

Salary.com Estimation for Associate Director Clinical Operations in Germantown, MD
$102,827 to $124,023
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