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Biologist II – Ligand Binding Assay

K3-Innovations, Inc.
Worcester, MA Full Time
POSTED ON 5/22/2026
AVAILABLE BEFORE 6/20/2026

Now Hiring: Biologist II – Ligand Binding Assay Bioanalyst

On-site: Worcester, MA


We are seeking a highly motivated Biologist II to join the Quantitative Translational and ADME Sciences (QTAS) department at AbbVie Bioresearch Center in Worcester, MA. This is an exciting opportunity to contribute to cutting-edge bioanalytical research supporting large-molecule therapeutics in drug discovery and early development.

Location: Worcester, MA (100% Onsite)

Contract Duration: 12 Months (possible extension based on performance and business needs)

Position: Biologist II


Position Overview

The Ligand Binding Assay (LBA) Operations Bioanalytical Team performs quantitative bioanalysis of large-molecule therapeutics including monoclonal antibodies (mAbs), ADCs, AOCs, fusion proteins, and bispecifics to support PK, PD, and TK studies.

The successful candidate will perform pre-clinical sample analysis using hybrid manual and automated ligand binding assays while supporting assay development, data reporting, and laboratory operations in a fast-paced and highly collaborative environment.


Key Responsibilities

  • Independently plan and execute bioanalytical sample analysis using multiple biological matrices including serum and tissue lysates
  • Perform ligand binding assays (PK, PD, TK, ADA) using Meso Scale Discovery (MSD) platforms
  • Generate high-quality bioanalytical data to support drug discovery and development programs
  • Analyze and interpret assay results and adjust analysis strategies as needed
  • Support ligand binding assay development, troubleshooting, validation, and transfer activities
  • Maintain accurate and timely documentation within ELN and rLIMS systems
  • Prepare, review, and report bioanalytical data packages for downstream analysis
  • Support laboratory operations including equipment maintenance and reagent/sample inventory management
  • Present experimental plans, data, and findings during team meetings and cross-functional discussions


Required Qualifications

  • Bachelor’s or Master’s degree in Biology, Chemistry, Pharmacology, or related scientific discipline
  • Minimum:
  • 2 years of pharmaceutical/biotechnology experience with an MS degree
  • 4 years of pharmaceutical/biotechnology experience with a BS degree
  • Hands-on experience with ligand binding assay workflows including ELISA and MSD platforms
  • Strong troubleshooting and problem-solving skills with the ability to adapt to shifting priorities
  • Ability to independently operate and maintain laboratory equipment
  • Strong written and verbal communication skills with technical reporting experience
  • Experience with data analysis software, Excel, ELN, and LIMS systems
  • Ability to work effectively within a multidisciplinary and collaborative environment


Preferred Qualifications

  • Experience independently developing ligand binding assays
  • Experience with laboratory automation systems and workflows
  • Experience supporting bioanalytical operations within pharmaceutical or biotechnology environments


Why Join This Opportunity?

  • Support innovative biologics and large-molecule therapeutic programs
  • Work with advanced bioanalytical technologies and automated laboratory systems
  • Collaborate within a highly scientific and multidisciplinary research environment
  • Gain valuable exposure to translational sciences and early drug development initiatives

Salary.com Estimation for Biologist II – Ligand Binding Assay in Worcester, MA
$99,286 to $118,528
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