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Director, National Accounts (DNA)

Ionis Pharmaceuticals, Inc.
Carlsbad, CA Full Time
POSTED ON 4/10/2026
AVAILABLE BEFORE 5/21/2026
Headquartered in Carlsbad, California, and with offices in Boston, Massachusetts, and Dublin, Ireland, Ionis has been at work for more than three decades discovering medical breakthroughs that have redefined life for people with serious diseases. We’re pioneers in RNA-targeted medicines, and our platform continues to revolutionize drug discovery and transform lives for patients with unmet needs. With multiple marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient needs, we continue to drive innovation in RNA therapies in addition to advancing new approaches in gene editing to provide greater value to patients and are well positioned financially to deliver on our strategic goals.

At Ionis, we pride ourselves on cultivating a challenging, motivating and rewarding environment that fosters innovation and scientific excellence. We know that our success is a direct result of the exceptional talents and dedication of our employees.

With an unprecedented opportunity to change the course of human health, we look to add diverse individuals, skill sets and perspectives to our exceptional team. We continue to invest time, money and energy into making our onsite, hybrid and remote work environments a place where solid and lasting relationships are built and where our culture and employees can thrive.

We’re building on our rich history, and we believe our greatest achievements are ahead of us. If you’re passionate about the opportunity to have meaningful impact on patients in need, we invite you to apply and join us. Experience and contribute to our unique culture while you develop and expand your career!

DIRECTOR, NATIONAL ACCOUNTS (DNA)

Summary

The Director, National Account (DNA) is a US field-based position and is responsible for developing and leveraging relationships with business and clinical executives at PBMs/GPOs, National & Regional Commercial Plans, Medicare Health Plans, FFS State Medicaid, Managed Medicaid plans and targeted IDNs to secure and maintain access for IONIS’ existing and future products. The DNA is responsible for the development and implementation of strategic business plans that will optimize appropriate engagement, coverage, payment of and patient access to IONIS’ products. This position reports to the Head, Strategic Accounts. Experience with Regional Accounts within the Northeast is preferred.

Responsibilities

  • Assess strategic engagement and sales implications of short- and long-term actions with each payer customer and take action to move payer decisions in a direction that continue to open patient access to care with IONIS products.
  • Provides and presents the IONIS enterprise view of our pipeline with key decision makers at Commercial and Med D payers within market place.
  • Work collaboratively with Patient Services and Chanel/Distribution to ensure reimbursement confidence and unimpeded access to all in-line brands to FDA label.
  • Works closely with Value & Access, Marketing, Field Access Managers, Field Medical Directors, Government Affairs and Field Sales Leadership, to ensure consistent exchange of important payer information and messages that should be communicated.
  • Provides periodic market updates to Sales Management that link important provider, payer and health care reform trends and issues as well as documents initiatives and their outcomes.

Requirements

  • Bachelor's degree required; Master’s/advanced degree preferred.
  • At least 15 years field-based pharmaceutical/biotech Sales and/or Marketing experience with at least 8 years of direct managed care experience; National Account experience preferred.
  • Rare, orphan, specialty injectable, infused and oral therapy launch experience.
  • Extensive understanding of commercial and Part D managed care organizations and processes.
  • Solid history of building strong relationships with payer Medical and Pharmacy Directors (clinical and administrative), case managers, and other medical benefit managers.
  • Previous experience includes working with national headquarters of managed care organizations and executing pull/push-through and any approved contracting tactics to local offices of the national organizations, as well as initiatives with other large and local managed care organizations.
  • Must be able to work with minimal supervision and strategic independent thought.
  • Field-based. Requires greater than 50% travel.

Preferred Requirements

  • Established relationships with Pharmacy Directors and Medical Directors within key assigned accounts.
  • Therapeutic experience in rare disease strongly preferred.
  • Demonstrated knowledge of payer decision-making for formulary processes, coverage, coding, billing, and patient access to drugs, biologicals, medical devices.
  • Experience providing appropriate insights and inputs within development of payer PAs and, or Medical Policy.
  • Exceptional communication skills that include verbal, written and presentation abilities.
  • Demonstrated problem-solving capabilities.
  • Experience negotiating contracts and agreements.
  • Outstanding consultative and networking capabilities.
  • Excellent project management skills, with the ability to handle multiple tasks at one time.
  • Ability to skillfully negotiate in tough situations with both internal and external groups.
  • Understanding of organizational behavior, corporate culture and be able to flourish in a complex and rapidly evolving workplace.
  • Skill to successfully lead account teams through collaboration with other members within and across sales, marketing, reimbursement and other business groups to improve overall effectiveness.

Please visit our website, http://www.ionis.com for more information about Ionis and to apply for this position; reference requisition # IONIS003954

Ionis offers an excellent benefits package! Follow this link for more details: Ionis Benefits

Full Benefits Link: https://www.ionis.com/careers/working-at-ionis/#:~:text=our employee spotlight-,Benefits,-Employees are rewarded

The pay scale for this position is $230,000 to $258,000

NO PHONE CALLS PLEASE. PRINCIPALS ONLY.

Ionis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.

Salary : $230,000 - $258,000

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