Demo

Principal Process Engineer

Insight Global
Wilson, NC Full Time
POSTED ON 6/26/2026
AVAILABLE BEFORE 7/24/2026

Day to day:

We are seeking experienced Principal Process Engineers to support a large-scale, greenfield biologics manufacturing project in the Raleigh-Durham surrounding area. These roles will function as process system owners, driving the design, implementation, and startup of critical manufacturing systems. This is a highly technical, hands-on role focused on engineering ownership across the full lifecycle — from design and requirements definition through startup and operational support — rather than traditional CQV execution.

Key Responsibilities

  • Serve as process system owner / SME for assigned manufacturing areas
  • Partner with A&E firms, EPCM teams, and equipment vendors to support design, build, and implementation
  • Lead process design, requirements definition (URS/FRS), and technical decision-making
  • Support equipment selection, system integration, and commissioning/startup activities
  • Provide hands-on troubleshooting and technical support during startup and early operations
  • Drive technology transfer and process fit-to-plant alignment
  • Collaborate cross-functionally with Manufacturing, Quality, Engineering, and Automation
  • Lead or support risk assessments, deviation investigations, and continuous improvement efforts
  • Ensure alignment with GMP and regulatory requirements
  • Contribute to “right first time” startup execution across capital projects


What Success Looks Like

  • Engineers who can step in and own systems end-to-end, not just execute validation
  • Ability to reduce team bandwidth constraints by driving specialization
  • Strong contributors to design, build, and startup phases of the program


Leadership & Collaboration

  • Ability to operate as a technical lead across multiple stakeholders
  • Strong communication and cross-functional collaboration skills
  • Experience working with external partners (EPCM, vendors, integrators)
  • Capable of owning systems end-to-end and driving accountability


Must Haves:

  • 5 years of experience in process engineering ownership within GMP environment (not CQV focused)
  • Proven ability to troubleshoot complex process systems & develop design concepts into technical requirements
  • Process Ownership experience in one of the 4 core areas:
  • Clean Utilities
  • CIP and Valve Arrays
  • In-Line Dilution Skids and Caustic Systems
  • Process Gases
  • Upstream
  • Junior Bioreactor Engineer (as a backup to our main engineer)
  • Downstream
  • Chromatography depth/nano filtration (potentially more than one)
  • Process Support
  • Washers Autoclaves
  • Freezers / Coldrooms
  • Experience in greenfield or large-scale brownfield GMP facilities strongly preferred or at least experience supporting large scale capital projects / construction driven environments
  • Bachelor’s degree in Engineering Discipline
  • Experience with DeltaV


Preferred:

  • Advanced degree (MS/MBA/PhD)
  • Lean / Six Sigma experience


Salary : $60 - $80

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