Senior Project Management Specialist

Join Immatics and shape the future of cancer immunotherapy; one patient at a time!

Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME, a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics.

Why Join Us?

• Innovative Environment: Help to pioneer advancements in cancer immunotherapy.
• Collaborative Culture: Be part of a diverse team dedicated to your professional growth.
• Global Impact: Contribute to therapies that make a lasting impact on patients globally.

We are seeking a Senior Project Management Specialist (Patient Journey Navigator function) to manage patient journeys from informed consent through treatment and first scan in our Phase 3 trial. This role coordinates time-critical patient cases across clinical sites and Immatics’ cross-functional teams to ensure efficient progression through the vein-to-vein (V2V) journey. The Senior Specialist works closely with site staff to support timely, compliant patient advancement. Success requires strong organizational skills, a solution-oriented mindset, and the ability to quickly understand clinical trial protocols, particularly in melanoma and TCR-T/TIL therapies.

Reports to: Senior Director, Project Management

Location: Fully Remote or Based in Houston. TX

Salary Range: $95,000 - $110,000

Basic Qualifications:

• Bachelor’s degree in life sciences, medicine, pharmacy, health sciences, or a related field
• 3 years of experience in clinical operations, medical affairs, or a related function within immunology and/or oncology
• Demonstrated experience coordinating cross-functional stakeholders and managing complex, time-sensitive projects
• Proven ability to interpret and apply clinical trial protocols while maintaining compliance in a regulated environment

Preferred Qualifications:

• Master’s degree in life sciences, medicine, pharmacy, health sciences, or a related field
• Experience in cell and gene therapy, particularly within clinical development settings
• Proficiency in project management methodologies and tools in a clinical or regulated environment
• Experience with strategic planning, risk management, and change management
• Advanced ability to solve complex operational challenges in regulated clinical environments
• Experience coordinating cross-functional teams and driving alignment across stakeholders

In this Role you Will:

• Lead site touchpoint calls, document key updates, and coordinate next steps to support timely patient progression and randomization
• Align cross-functionally with internal stakeholders to ensure consistent, accurate guidance is provided to sites
• Manage and adapt patient journeys in real time based on individual needs and site constraints, following the defined V2V pathway
• Drive end-to-end patient workflows to achieve rapid, compliant progression pre- and post-randomization
• Coordinate key milestones including eligibility, randomization, and manufacturing timelines with internal teams
• Provide sites with clear guidance on required EDC completion and support issue resolution, including out-of-specifications communication
• Serve as a responsive, reliable point of contact for site stakeholders, including availability outside standard hours

Travel required:

• If remote: Regular travels to Houston or a specific site for PI engagement might be required ~10/year
• If Houston: Limited travels to site for PI engagement might be required ~3/year

Qualified candidates will participate in a structured interview process, which includes:

• An initial recruiter phone screen (conducted via video)
• A recruiter-facilitated introduction and interview with the hiring leader and key stakeholders (via video)
• A final-stage interview, which may include an in-person meeting at our U.S. Headquarters in Houston, TX

Work authorization/security clearance requirements:

Legal eligibility to work in the United States is required. Immatics participates in E-Verify and all new employees will be subject to the Department of Homeland Security requirements for employment

Affirmative Action/EEO statement:

Immatics is an equal opportunity employer. All employment decisions including the decision to hire, promote, discipline, or discharge, will be based on merit, competence, performance, and business needs.

What do we offer?

At Immatics, we believe in investing in our team’s health, safety and well-being. Here’s what you can expect if you join Immatics

Comprehensive Benefits:

• Competitive rates for Health, Dental, and Vision Insurance
• 4 weeks of Paid Time off, granted up front each year and prorated for first and last year of employment.
• Sick Time Off – 7 days
• 12 Paid Holidays
• 100% Employer-Paid Life Insurance up to at 1x annual salary, up to one hundred thousand dollars
• 100% Employer Paid Short- and Long-Term Disability Coverage
• 401(k) with Immediate Eligibility & company match…
• You are eligible for 401(k) plan participation as of your first paycheck.
• The company will match 100% of your contributions up to 3% of your base salary for the first two years of employment, 4% for years 2-3 of employment, and up to 5% of your salary from the fourth year onward of continued employment.
• Partially paid Parental Leave for eligible employees. (3 weeks)
• Additional voluntary employee paid coverages including Accident, Hospital Indemnity, and Critical Illness Employee Paid Identity Theft Protection and Pet Insurance.