Senior Manufacturing Associate - Second Shift

Join Immatics and shape the future of cancer immunotherapy; one patient at a time!

Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME, a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics.

Why Join Us?

• Innovative Environment: Help to pioneer advancements in cancer immunotherapy.
• Collaborative Culture: Be part of a diverse team dedicated to your professional growth.
• Global Impact: Contribute to therapies that make a lasting impact on patients globally.

Role Overview

We are seeking a Senior Manufacturing Associate to support our CMC-GMP Manufacturing team. In this role, you will lead and execute complex, time-sensitive cell processing and testing activities for patient-derived cellular products in a clinical manufacturing environment. You will be responsible for ensuring compliance with GMP standards, maintaining product integrity and sterility, and overseeing accurate documentation and batch execution. As a senior team member, you will also provide technical guidance, support process improvements, and contribute to maintaining high operational standards across manufacturing activities.

Schedule: 1430 – 2300; Monday to Friday

Reports to: Manufacturing Manager

Location: 13203 Murphy Road Suite 100 Stafford, TX 77477

Basic Qualifications:

• Associate’s or Bachelor’s degree in a scientific field (e.g., biology, biotechnology, or related discipline)
• 4 years of experience in GMP-regulated manufacturing, preferably in cell therapy or biologics
• Demonstrated experience executing aseptic processing and working in cleanroom environments (Grade A–D)
• Proven ability to maintain compliant documentation in accordance with ALCOA and cGDocP standards
• Experience identifying deviations and supporting investigations, CAPAs, and quality systems

Preferred Qualifications:

• Bachelor’s degree in a scientific field
• Experience in cell therapy manufacturing, including cell culture, cryopreservation, and cell processing techniques
• Familiarity with GLP, GTP, and industry standards (e.g., FACT, CAP, CLIA)
• Experience supporting validation activities (IQ/OQ/PQ) and change control processes
• Advanced troubleshooting skills and ability to resolve complex manufacturing or equipment issues
• Experience mentoring or training junior staff and contributing to team development
• Demonstrated ability to drive process improvements in a GMP-regulated environment

In this role you will:

• Execute and verify cell processing activities, including cell culture, enrichment, cryopreservation, thawing, and washing
• Perform manufacturing operations in compliance with GMP, GLP, GTP, and applicable regulatory standards
• Maintain accurate, compliant documentation and batch records in line with ALCOA and cGDocP requirements
• Ensure aseptic handling and cleanroom compliance to maintain product sterility and integrity
• Identify, document, and support investigation of deviations, including CAPA implementation
• Perform calculations, equipment maintenance, and routine manufacturing support activities
• Lead manufacturing runs, mentor junior team members, and contribute to continuous improvement initiatives

What do we offer?

At Immatics, we believe in investing in our team’s health, safety and well-being. Here’s what you can expect if you join Immatics:

Comprehensive Benefits:

• Competitive rates for Health, Dental, and Vision Insurance
• 4 weeks of vacation, granted up front each year and prorated for first and last year of employment.
• 12 company paid holidays
• 7 days of sick time
• 100% employer-paid life insurance up to at 1x annual salary, up to one hundred thousand dollars
• 100% employer-paid short- and long-Term disability coverage
• 401(k) with immediate eligibility and company match…
• The company will match 100% of your contributions up to 3% of your base salary for the first two years of employment, 4% for years 2-3 of employment, and up to 5% of your salary from the fourth year onward of continued employment.
• Partially paid parental leave for eligible employees.
• Additional voluntary employee-paid benefits and services, including accident, hospital indemnity, and critical illness insurance, as well as identity theft protection and pet insurance.

Equal Employment Opportunity

We are an equal opportunity employer and are committed to building a diverse and inclusive workplace. We consider all qualified applicants for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, national origin, ancestry, age, marital status, disability, genetic information, veteran status, or any other status protected by applicable law.

Reasonable Accommodations

We are committed to providing reasonable accommodations to individuals with disabilities and to applicants with sincerely held religious beliefs, practices, or observances. If you require assistance or accommodation during the application or interview process, please contact us at PRIOR:

Work authorization/security clearance requirements

Legal eligibility to work in the United States is required. Immatics participates in E-Verify and all new employees will be subject to the Department of Homeland Security requirements for employment

Affirmative Action/EEO statement

Immatics is an equal opportunity employer. All employment decisions including the decision to hire, promote, discipline, or discharge, will be based on merit, competence, performance, and business needs.