Analytical Chemistry Associate

We are seeking a motivated and detail-oriented Analytical Chemistry Associate to join our growing laboratory team in Columbia, MO. This is a full-time, on-site position (40 hours/week) focused on chromatographic analysis and instrumental method execution in a regulated laboratory environment. The ideal candidate has hands-on experience operating HPLC and LC/MS instrumentation and thrives in a structured, compliance-driven setting.

Key Responsibilities

• Operate, maintain, and troubleshoot HPLC and LC/MS instrumentation for routine analytical testing
• Execute analytical methods for purity, identity, and quantitation of small molecules and biologics
• Perform UV/Vis spectrophotometric analyses as part of routine sample characterization
• Generate and review analytical data with attention to accuracy, traceability, and regulatory compliance
• Author and execute test records, logbooks, and batch records in accordance with cGMP standards
• Maintain instrument qualification records, calibration logs, and preventive maintenance schedules
• Participate in method validation and transfer activities as needed
• Support wet lab activities including sample preparation, standard preparation, and reagent management
• Assist with microbiological and bioanalytical testing as assigned (endotoxin, sterility, microbial enumeration)
• Communicate results clearly in written reports and during team meetings
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Required Qualifications

• Bachelor's degree in Chemistry, Biochemistry, or a closely related field
• Minimum 1-2 years of direct, hands-on experience operating HPLC instrumentation
• Demonstrated experience with LC/MS (single quadrupole or equivalent) in an analytical setting
• Proficiency in data acquisition and processing software (e.g., Agilent ChemStation, OpenLAB, or equivalent)
• Strong understanding of analytical principles including chromatographic separation, UV detection, and mass spectrometry fundamentals
• Excellent attention to detail and commitment to data integrity
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Preferred Qualifications

• Master's degree in Chemistry, Biochemistry, or related discipline
• Experience working in a cGMP-regulated laboratory environment (pharmaceutical, biotech, or contract lab)
• Hands-on experience with UV/Vis spectrophotometry
• Experience with lyophilization (freeze-drying) processes and/or lyophilized product characterization
• Familiarity with wet lab techniques, including:
• Endotoxin testing (LAL/BET methods per USP <85>)
• Sterility testing (USP <71> or equivalent)
• Microbiology experiments including microbial enumeration (TAMC/TYMC, USP <61>)
• Familiarity with USP, Ph. Eur., or ICH guidelines
• Experience writing or executing SOPs, test methods, or validation protocols
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Work Schedule and Location

• Location: Columbia, MO (on-site required)
• Schedule: Full-time, 40 hours/week
• Benefits: This position does not include a benefits package
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Compensation

Salary is commensurate with experience. Based on current market data for analytical chemistry roles in the Columbia, MO area:

• Bachelor's level / Entry to mid-level: $52,000 - $68,000/year
• Master's level or significant cGMP experience: $68,000 - $85,000/year

Final compensation will reflect education, years of relevant experience, and instrument proficiency.