Demo

MES Project Manager

GyanSys Inc.
Evansville, IN Contractor
POSTED ON 1/6/2026
AVAILABLE BEFORE 2/4/2026

GyanSys is looking for a MES Project Manager for its direct client.


The MES Project Manager will be responsible for leading the implementation of the Manufacturing Execution System (MES) across assigned manufacturing sites.


Key Responsibilities:

  • Lead end-to-end MES project lifecycle at assigned site(s): initiation, planning, execution, validation, go-live, hyper care.
  • Develop and maintain project plans, risk registers, and status reports.
  • Manage project scope, budget, and schedule, escalating issues as needed.
  • Coordinate with global program team to ensure alignment with global template and governance.
  • Ensure MES system design aligns with global standards and local regulatory requirements (e.g., FDA 21 CFR Part 11, EU Annex 11, GMP).
  • Coordinate integration with ERP (SAP), LIMS, RedZone (OEE), and automation systems (PLC/SCADA).
  • Oversee system configuration, testing, validation (CSV), and data migration
  • Implement OCM activities: communication, engagement, and end-user adoption.
  • Ensure delivery of role-based training for operators, ǪA, and IT staff.
  • Support creation of site-specific SOPs aligned to MES processes.


Key Requirements:


  • 7 years of project management experience, with at least 3 years in MES or manufacturing IT systems.
  • Proven track record of delivering complex IT/OT projects in regulated industries (Pharma, FMCG, Food, Consumer Health).
  • Experience with MES platforms (e.g., Werum PAS-X, Siemens Opcenter, Rockwell PharmaSuite, AspenTech, etc.).
  • Strong project management skills (PMP certification preferred).
  • Deep understanding of manufacturing processes (batch, packaging, serialization).
  • Knowledge of regulatory compliance (GxP, 21 CFR Part 11, Data Integrity).
  • Bachelor’s degree in engineering, IT, Computer Science, or related field.

About GyanSys


GyanSys is a leading global system integrator company supporting enterprise customers worldwide. We specialize in solutions implementations, managed services, and data analytics spanning SAP, Salesforce, Microsoft, and other prime enterprise platforms. Using a mature blended delivery model with over 3,000 consultants, we support over 350 enterprise customers across the Americas, Europe, and APAC.

Hourly Wage Estimation for MES Project Manager in Evansville, IN
$48.00 to $59.00
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