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Associate Technical Product Manager

Guardant Health
Palo Alto, CA Full Time
POSTED ON 12/27/2025
AVAILABLE BEFORE 2/2/2026
Company Description

Guardant Health is a leading precision oncology company focused on guarding wellness and giving every person more time free from cancer. Founded in 2012, Guardant is transforming patient care and accelerating new cancer therapies by providing critical insights into what drives disease through its advanced blood and tissue tests, real-world data and AI analytics. Guardant tests help improve outcomes across all stages of care, including screening to find cancer early, monitoring for recurrence in early-stage cancer, and treatment selection for patients with advanced cancer. For more information, visit guardanthealth.com and follow the company on LinkedIn, X (Twitter) and Facebook.

Essential Duties And Responsibilities

Product Execution & Operations

  • Manage day-to-day product operations for the liquid assay, ensuring consistent quality, availability, and timely updates to internal teams.
  • Manage cross-functional coordination with Operations, Supply Chain, Quality, and Clinical Lab teams to resolve issues impacting assay performance or delivery.
  • Support product lifecycle activities, including change management, design updates, and process optimizations.
  • Partner with Product Director and Engineering to translate assay performance data and feedback into actionable improvements.
  • Track and communicate key product KPIs, operational metrics, and quality indicators to leadership.

Technical & Product Management

  • Serve as a liaison between product management, engineering, bioinformatics, and operations teams.
  • Understand and articulate the technical details of the liquid assay, including workflow dependencies, automation components, and data pipeline impacts.
  • Support the execution of new product introductions, product line extensions, and assay optimization initiatives.
  • Contribute to requirements gathering, validation planning, and release readiness reviews.
  • Ensure documentation, specifications, and process updates are maintained accurately and in compliance with quality systems.

Cross-Functional Collaboration

  • Partner closely with the Product Director to align tactical operations with strategic goals.
  • Collaborate with Regulatory, Clinical, and Quality teams to ensure compliance with applicable standards and readiness for audits or submissions.
  • Work with Commercial Operations and Customer Support to address post-launch feedback, product issues, and customer escalations.

Qualifications

  • Typically requires a Bachelor's degree in life sciences, bioengineering, molecular biology, or related technical field (advanced degree preferred).
  • 5 years of related experience; 3 years with a Master’s degree or PhD
  • Understanding of diagnostic assay workflows and experience in regulated environments (IVD, CLIA, CAP, or FDA-regulated labs).
  • Proven ability to drive execution, manage complex cross-functional projects, and deliver under tight timelines.
  • Exceptional communication, organization, and analytical skills.
  • Experience supporting NGS-based assays or liquid biopsy platforms.
  • Familiarity with oncology diagnostics.
  • Prior experience in product operations or lifecycle management for diagnostics or medical devices.
  • PMP, Agile, or Lean Six Sigma certification is a plus.

Hybrid Work Model: This section is applicable to onsite employees who are eligible for hybrid work location as specified by management and related policies. Guardant has defined days for in-person/onsite collaboration and work-from-home days for individual-focused time. All U.S. employees who live within 50 miles of a Guardant facility will be required to be onsite on Mondays, Tuesdays, and Thursdays. We have found aligning our scheduled in-office days allows our teams to do the best work and creates the focused thinking time our innovative work requires. At Guardant, our work model has created flexibility for better work-life balance while keeping teams connected to advance our science for our patients.

The annualized base salary ranges for the primary location and any additional locations are listed below. This range does not include benefits or, if applicable, bonus, commission, or equity. Each candidate’s compensation offer will be based on multiple factors including, but not limited to, geography, experience, education, job-related skills, job duties, and business need. Primary Location: Palo Alto, CA Primary Location Base Pay Range: $108,500 - $149,200 Other US Location(s) Base Pay Range: $92,200 - $126,850 If the role is performed in Colorado, the pay range for this job is: $97,700 - $134,250

Employee may be required to lift routine office supplies and use office equipment. Majority of the work is performed in a desk/office environment; however, there may be exposure to high noise levels, fumes, and biohazard material in the laboratory environment. Ability to sit for extended periods of time.

Guardant Health is committed to providing reasonable accommodations in our hiring processes for candidates with disabilities, long-term conditions, mental health conditions, or sincerely held religious beliefs. If you need support, please reach out to Peopleteam@guardanthealth.com

A background screening including criminal history is required for this role. GH will consider qualified applicants with criminal arrest or conviction histories in a manner consistent with applicable law including but not limited to the LA County Fair Chance Policies and the Fair Chance Act (Gov. Code Section 12952).

Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

All your information will be kept confidential according to EEO guidelines.

To learn more about the information collected when you apply for a position at Guardant Health, Inc. and how it is used, please review our Privacy Notice for Job Applicants.

Please visit our career page at: http://www.guardanthealth.com/jobs/

Salary : $92,200 - $149,200

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