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Senior Infrastructure Engineer

GSK and Careers
Collegeville, PA Full Time
POSTED ON 2/10/2026 CLOSED ON 3/9/2026

What are the responsibilities and job description for the Senior Infrastructure Engineer position at GSK and Careers?

Site Name: USA - Pennsylvania - Upper Providence
Posted Date: Feb 6 2026


The Onyx Research Data Platform organization represents a major investment by GSK R&D and Digital & Tech, designed to deliver a step-change in our ability to leverage data, knowledge, and prediction to find new medicines. We are a full-stack shop consisting of product and portfolio leadership, data engineering, infrastructure and DevOps, data / metadata / knowledge platforms, and AI/ML and analysis platforms, all geared toward:

  • Building a next-generation data experience for GSK’s scientists, engineers, and decision-makers, increasing productivity and reducing time spent on “data mechanics”

  • Providing best-in-class AI/ML and data analysis environments to accelerate our predictive capabilities and attract top-tier talent

  • Aggressively engineering our data at scale to unlock the value of our combined data assets and predictions in real-time

A Senior Infrastructure Engineer is a leading technical contributor who can consistently take a loosely defined business or technical requirement, architect and build it to a well-defined specification, and execute on it at a high level. They have a strong focus on metrics, both for the impact of their work and for its inner workings / operations.

A Senior Infrastructure Engineer should be deeply familiar with the tools of their specialization and of their customers and engaged with the open-source community surrounding them – potentially, even to the level of contributing pull requests.

Key responsibilities for the Senior Infrastructure Engineer include:

  • Broad and deep knowledge of Linux systems administration, storage (e.g. Weka/ZFS) and network configuration

  • Design, build, and operate tools, services, workflows etc that deliver high value, through the solution to key business problems

  • Work to transition from classical HPC ways of working to a modern "private cloud" approach that focuses on Infrastructure-as-Code, DevOps-driven workflows, and containerization, and helps put site reliability engineering and automation at the core of every running Onyx service

  • Implement and maintain observability stack and processes for infrastructure (Grafana, Prometheus, InfluxDB) across all of HPC and other computing components

  • Own the schedulers (e.g. Slurm) and processes that continually improve users' access to resources in the most efficient way

  • Provide input into the roadmaps of teams representing upstream dependencies, to help improve the overall program of work

  • Fully versed in coding best practices and ways of working, and participates in code reviews/partnering to improve the team's standards

  • Design innovative strategy beyond the current enterprise way of working to create a better environment for the end users, and be able to construct a coordinated, stepwise plan to bring others along with the change curve

  • Provide thought leadership to team members to help others get the job done right, first time

Why you?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

  • Bachelor’s degree in Computer Science, Software Engineering, or related discipline

  • 4 years of Linux Systems Administration experience

  • Experience with modern software development tools / ways of working (e.g. git/GitHub, DevOps tools, metrics / monitoring…)

  • Experience with enterprise Linux hardware and software or troubleshooting and maintenance.

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

  • Deep knowledge and use of at least one common programming and scripting language: e.g., Python, Bash, including toolchains for documentation, testing, and operations / observability

  • Application experience of CI/CD implementations using git and a common CI/CD stack (e.g. GitLab, Azure DevOps)

  • Demonstrated excellence with agile software development environments using tools like Jira and Confluence

#LI-GSK #R&DTechProject

#GSKOnyx

Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at HR.AmericasSC-CS@gsk.com where you can also request a call.

Please note should your inquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receive

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

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