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Downstream Manufacturing Supervisor

Global Life Science Hub
Piscataway, NJ Full Time
POSTED ON 6/16/2026
AVAILABLE BEFORE 7/15/2026

Downstream Manufacturing Supervisor - Day & Night Shift Piscataway, NJ - Full-Time, Permanent

We are placing a Downstream Manufacturing Supervisor with a leading biologics manufacturer in Piscataway, NJ. Full-time, permanent position - not contract. Two positions available - day and night shift.


You will be leading a team of manufacturing associates executing downstream purification processes in a cGMP environment, overseeing batch execution at 50L to 1000L scale on live biosimilar programs.


What you'll be doing:

  • Supervising and mentoring downstream manufacturing associates across shift operations
  • Overseeing purification operations including chromatography, AKTA skids, and TFF systems
  • Ensuring batch execution runs to schedule - engineering, clinical, and commercial stage
  • Reviewing and approving batch records, deviations, and GMP documentation
  • Leading investigations and driving corrective actions arising from batch execution
  • Maintaining compliance with cGMP, EHS, and site quality standards
  • Coordinating with cross-functional teams including QA, engineering, and process development


What you need:

  • 1-2 years supervisory or team lead experience in a cGMP biologics manufacturing environment
  • Hands-on downstream manufacturing background - purification, chromatography, TFF
  • Experience at scale - 50L to 1000L purification operations
  • Comfortable owning GMP documentation, deviations, and compliance requirements
  • BS or MS in biological, biochemical, chemical, or related sciences


Relocation package available for the right candidate.


Apply directly or get in touch to discuss.

Salary : $45 - $53

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