Demo

Senior Scientist - Protein Expression

Gables Search Group
Rockville, MD Full Time
POSTED ON 9/13/2026
AVAILABLE BEFORE 11/5/2026
We are recruiting for a Senior Scientist with deep expertise in bacterial cell-free protein expression to join an innovative scientific team in Rockville, Maryland. This role offers the independence, resources, and cross-functional collaboration to advance protein expression technologies and drive meaningful research programs.

What You’ll Do

  • Lead development and optimization of bacterial cell-free protein expression workflows across a variety of protein targets
  • Improve extract preparation methods to increase protein yield, solubility, and functional activity
  • Design high-throughput screening strategies for constructs, chaperones, and reaction conditions
  • Analyze protein expression and quality using SDS-PAGE, Western blot, ELISA, capillary electrophoresis, and related methods
  • Troubleshoot complex expression challenges and recommend new technologies, platforms, and approaches
  • Lead scientific projects while partnering with multidisciplinary research teams
  • Document experimental results and contribute to SOPs, technical reports, and patent-related materials

What We’re Looking For

  • PhD in Biochemistry, Molecular Biology, Protein Science, or a closely related discipline
  • Hands-on expertise with bacterial cell-free protein synthesis, including optimization and troubleshooting
  • Strong knowledge of E. coli molecular biology, protein expression, and extract preparation
  • Experience with automated or high-throughput screening platforms
  • Strong protein characterization and analytical laboratory skills
  • Demonstrated ability to independently lead research initiatives and collaborate across scientific teams

Compensation

Base salary: $115,000-$135,000 plus bonus

Relocation assistance available

Salary : $115,000 - $135,000

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