Chief of Staff, U.S. AI Policy and Public Policy

We’re a philanthropic funder

that partners with leading donors

to multiply their impact.

Coefficient has directed over $5 billion in grants since 2014. Our mission is to help others as much as we can with the resources available to us.

About Us Partner With Us

Open Philanthropy is now Coefficient Giving. Read more.

Open Philanthropy is now Coefficient Giving. Read more.

Our Funds

• Abundance & Growth
  
  

Accelerating growth and scientific progress

• Air Quality
  
  

Improving health through cleaner air

• Biosecurity & Pandemic Preparedness
  
  

Building resilience against biological risk

• Effective Giving & Careers
  
  

Empowering people to maximize their impact

• Farm Animal Welfare
  
  

Improving the lives of farmed animals

• Forecasting
  
  

Improving how critical decisions are made

• Global Aid Policy
  
  

Encouraging generous and cost-effective aid

• Global Catastrophic Risks Opportunities
  
  

Countering threats to civilization

• Global Growth
  
  

Supporting growth to reduce global poverty

• Global Health & Wellbeing Opportunities
  
  

Improving health and wellbeing for all people

• Lead Exposure Action Fund
  
  

Accelerating progress toward a lead-free world

• Navigating Transformative AI
  
  

Ensuring AI is safe and well-governed

• Science and Global Health R&D
  
  

Supporting lifesaving ideas and discoveries

• Strep A Vaccine Fund
  
  

Accelerating development of Strep A vaccines

Strategic Cause Selection

We believe the most important decision a philanthropist makes is choosing which causes to support. We conduct in-depth research to identify the areas where our funding can help others the most.

How we select causes

Research & News

• 2025 Letter from the CEO
  
  

Coefficient Giving directed over $1 billion in 2025, the most in our history. This significant milestone is the result of extraordinary dedication from our funders, staff, and grantees, who share the conviction that effective philanthropy can be a powerful lever for making the world a much better place.

• Open Philanthropy Is Now Coefficient Giving
  
  

Our new name marks our next chapter as we double down on our longstanding goal of helping more funders increase their impact. We believe philanthropy can be a far more vital force for progress than it is today.

• Announcing the Strep A Vaccine Fund
  
  

Strep A causes over 600,000 deaths per year — a toll comparable to HIV/AIDS and malaria — but attracts a tiny fraction of the research funding. Today, we're launching the Strep A Vaccine Fund: a multi-donor initiative to accelerate the development of Strep A vaccines.

Featured Grants

• Science and Global Health R&D
  
  

Using AI to create more effective vaccines

Professors David Baker and Neil King use advanced protein modeling software and nanoparticle technology to develop better vaccines. Their approach has already led to an approved COVID-19 vaccine and more effective flu vaccine that has completed Phase I trials. David Baker won the Nobel Prize in Chemistry in 2024.

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• Effective Giving & Careers
  
  

Helping people find high-impact careers

Four professionals share how our career advising grantees — Probably Good, High Impact Medicine, and High Impact Professionals — helped them find paths to greater impact.

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• Science and Global Health R&D
  
  

Transforming tuberculosis testing through a low-cost device

Saad Bhamla is a key figure in the frugal innovation movement, which seeks to build cheaper versions of existing scientific tools. His latest innovation, a portable device to test tuberculosis and other diseases, could well be another consequential contribution to global public health.

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• Lead Exposure
  
  

Eliminating lead paint, one country at a time

In dozens of low- and middle-income countries, much of the paint supply contains dangerous amounts of lead. The Lead Exposure Elimination Project is working to end this public health crisis, which has received little attention from the global health community relative to its devastating effects.

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• Farm Animal Welfare
  
  

Freeing hundreds of millions of chickens from cages

The Open Wing Alliance (OWA), a coalition of advocacy groups, has persuaded more than 3,000 food companies worldwide to shift to using cage-free eggs, through a mix of negotiation and public campaigns. Thanks to OWA and other advocates, over 250 million hens have been spared from confinement.

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