Demo

Principal Investigator (MD)

Discover International
Chicago, IL Full Time
POSTED ON 6/17/2026
AVAILABLE BEFORE 7/6/2026

Job Description

We are partnered with a well-established, multi-site clinical research organization that is actively expanding and hiring Principal Investigators across multiple locations across the United States.


This opportunity is open to Board-Certified or Board-Eligible physicians, including those with no prior clinical research experience, who are interested in participating in clinical trials within a fully supported research environment. The organization conducts Phase I through Phase IV clinical trials across multiple therapeutic areas and provides comprehensive operational, regulatory, and research staff support.


Multiple openings are available nationwide due to continued growth.


Key Responsibilities

  • Serve as Principal Investigator on assigned clinical trials in compliance with ICH-GCP, FDA regulations, and sponsor protocols
  • Oversee study conduct, subject safety, and data integrity
  • Ensure protocol adherence and regulatory compliance
  • Collaborate with Sub-Investigators, Study Coordinators, and research staff
  • Participate in sponsor, CRO, and monitor visits as required
  • Maintain accurate and complete regulatory documentation


Required Qualifications

  • MD or DO degree
  • Active, unrestricted medical license in the state where you reside and practice
  • Board Certified or Board Eligible in Internal Medicine, Family Medicine, Rheumatology, or a related specialty
  • No prior Principal Investigator or clinical research experience required
  • Strong interest in clinical research and patient care
  • Ability to meet required on-site time commitments


Preferred Experience (Not Required)

  • Prior experience as a Principal Investigator or Sub-Investigator
  • Familiarity with FDA-regulated clinical research environments

Salary.com Estimation for Principal Investigator (MD) in Chicago, IL
$94,334 to $125,436
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