What are the responsibilities and job description for the Principal Investigator position at Connect Life Sciences?
Summary
We are seeking a full-time Physician to serve as a Principal Investigator (PI) for clinical trials at our Houston, TX site. The PI will oversee and conduct research activities, ensuring compliance with study protocols, regulatory requirements, and ethical guidelines.
Responsibilities include providing clinical oversight, monitoring patient safety, and collaborating with research staff to advance clinical studies. Ideal candidates will have two or more years of clinical experience in family medicine or internal medicine and experience caring for patients presenting with SLD, MASH, and Alzheimer's/Dementia. Candidates must possess strong analytical skills and a dedication to advancing clinical research through high-quality patient care and ethical study practices.
The PI assumes overall responsibility for the conduct of the study and agrees to:
• Personally conduct or supervise the research
• Ensure that each delegated individual is qualified by education, training, and experience
• Protect the rights, safety, and welfare of study participants
The PI further agrees that the research:
• Is conducted in accordance with all federal regulatory requirements and applicable state law
• Is conducted in accordance with the IRB-approved plan
• Maintains accuracy, security, and integrity of research data and its subsequent analysis
Duties and Responsibilities
• Review and maintain expert knowledge of study-related activities and protocols
• Assume all responsibilities and obligations as an Investigator per Title 21 Part 312 and FDA Form 1572
• Adhere to study protocols, FDA regulations, and Good Clinical Practice (GCP) at all times
• Maintain sponsor and clinical trial confidentiality
• Perform study-related procedures including physical examinations, informed consent, subject history, adverse event review, test article handling, appointment scheduling, records review, treatment coordination, collection of vital signs, and subject health assessments
• Review and adjudicate lab, imaging, and biopsy findings
• Assist in preparation for study monitor visits
• Perform subject screening and recruitment
• Provide some weekend coverage to facilitate protocol-required study visits
• Provide after-hours phone coverage as needed
Qualifications
• Clinical research experience highly preferred but not required
• One to two years of clinical practice in Internal Medicine, Family Medicine, Alzheimer’s, Dementia, or Obesity
Knowledge, Skills, and Abilities
• Possess impeccable integrity and strong personal and professional values consistent with high standards and mission
• Comply with company policies, code of ethics, and guiding values at all times