Bioanalytical Chemist

Cogent Scientific, an insourced contract research organization, is looking for the right people to accomplish our Mission: to support the life sciences industry with specialized laboratory services delivered by professional scientists—advancing research, fostering collaboration, and accelerating innovation with quality and a commitment to excellence.  We can offer you the chance to build on your skills and knowledge while working among experts in their fields and with cutting-edge instrumentation.

Cogent Scientific offers competitive pay (with relocation bonus as needed), attractive benefits (such as medical/dental/vision insurance; 401(k); parental leave; PTO and paid holidays; etc.) and an exciting work environment.  We aim to recruit the best people who stand out among their peers and embody our Core Values:

• Client Focused: We only succeed when our clients succeed.
• Outstanding: We deliver meticulous results through outstanding performance.
• Good: We act ethically and morally.
• Employee-Centric: We honor and support our employees.
• Nimble: We are prepared to adapt in an ever-changing industry.
• Team-Oriented: We collaborate with each other and with our clients.

We currently have a role available for a Bioanalytical Chemist at our South San Francisco site.

Job duties include, but are not limited to:

• Support Bio-Analysis sample preparation, design and perform mass-spec analysis as well as data analysis/interpretation from in-vivo studies from triple-quad mass spectrometers (Sciex 7500).
  • Experience operating, maintaining Sciex 7500 Qtrap, triple-quad mass spectrometers, or Orbitrap instruments is required.
  • Must be able to work independently to design and execute experiments, and has a track record of conceiving creative solutions in the lab to answer complex questions.
  • Must be proficient in troubleshooting mass spec and LC systems from common vendors.
  • Experience with cell culture, PK, and Bio-Analysis of ADC drugs from complex matrices (plasma, tissue).

• Characterization of recombinant proteins, antibodies, and ADCs using intact-MS and peptide mapping for routine QC using high-res mass spec platforms (Oribtrap).
  • Must have a minimum of 2-5 years of hands-on laboratory experience working with mass spectrometry focused approaches in a discovery setting to support drug development.
  • Extensive hands-on experience operating and maintaining LCMS instrumentation as well as SEC/HIC or U/HPLC systems, and proficient in the software used for data analysis (Protein Metrics, Skyline, Biopharma Finder) is required.
  • Experience in analytical characterization using SEC/HIC, U/HPLC, cIEF, CE, as well as experience running nano-LCMS instruments for proteomics is desirable.
• Work closely with a team of scientists to support the development, optimization, and execution of analytical assays for protein characterization and bioanalysis to guide large molecule therapeutic design.
  • Experience with high throughput plate-based assays working on both large and small molecules is beneficial.
• Collaborate with the team to meet timelines and deliverables.
  • The successful candidates demonstrates a "can-do" attitude and brings innovative ideas to challenging projects to contribute to a collaborative and cross-functional organization
• Perform general lab maintenance and instrument calibrations.
  • Must be experienced with molecular biology, analytical techniques, and general lab practices, and presenting and interpreting complex datasets in Excel and Prism.
• Maintain a high level of productivity in a laboratory setting, this role is 100% on site in South San Francisco and is lab based, but will have opportunities to represent data with project teams.
  
  • Experience with analyzing and reporting analytical data, presenting data to colleagues and collaborators, and being a subject area expert in mass spec and analytical approaches is highly advantageous.
  • Experience with R for data visualization is advantageous.

Job requirements include, but are not limited to:

• Minimum of a BSc with 2-5 years industry experience or MSc with 1-2 years industry experience in a mass spec focused lab on antibodies/ADCs/ proteomics or in a relevant scientific discipline focused on mass spec and ADCs.
  
• Team player mentality with strong written and verbal communication skills. Must have good organizational skills and must be detail oriented. 
• The ideal candidate will be enthusiastic and self-motivated, with the strong interpersonal, communication, and organizational skills necessary to operate effectively in a fast-paced multidisciplinary environment with flexibility and an adaptable approach to goal delivery.

Cogent Scientific provides equal employment opportunities to all applicants and does not discriminate based on any legally protected characteristic.

Additionally, if you require a reasonable accommodation during the application or interview process, please let us know.

This job posting will close by 4/30/2026 or when a candidate is identified, whichever comes first.

Salary : $90,000 - $95,000