Senior Research Associate

Skills: Cell Based Assays, Invitro Characterization, ELISA, Flow

Senior Research Associate – Antibody Discovery and Cell Biology

Position Summary

We are seeking a highly motivated Senior Research Associate to drive antibody characterization and cell-based functional assays in support of our therapeutic discovery programs. This individual will take a lead role in evaluating antibody leads received from CRO partners, developing in-vitro assays, and optimizing experimental workflows. They will work closely with the Director of Antibody Discovery and Protein Sciences and contribute to both scientific execution and lab coordination in a collaborative startup environment. This position will also support other cell and molecular biology teams as needed and work in a matrixed environment.

Key Responsibilities

• Lead in-vitro characterization of antibody leads from CROs, including binding, potency, and functional activity assessments.
• Develop, optimize, and execute biochemical and cell-based assays (e.g., ELISA, SPR/BLI, FACS, reporter and signaling assays) to support antibody selection and optimization.
• Culture, maintain, and engineer mammalian cell lines for assay development and screening.
• Express, purify, and analyze recombinant antibodies and proteins as needed for internal studies.
• Analyze, interpret, and present experimental data to project teams and leadership.
• Coordinate with CROs to manage study timelines, sample logistics, and data quality.
• Contribute to assay transfer and troubleshooting across internal and external teams.
• Maintain accurate and detailed experimental records in electronic laboratory notebooks.
• Support lab operations, including reagent preparation, equipment oversight, and inventory management.
• Provide training and day-to-day guidance to junior staff or interns.
• Participate in experimental design discussions and help shape assay and workflow strategy.

Qualifications

• Bachelor’s or Master’s degree in Molecular Biology, Cell Biology, Biochemistry, Immunology, or a related field.
• 4–8 years of relevant biotech or biopharma experience with demonstrated independence in assay development and data interpretation.
• Hands-on experience with antibody or protein characterization (ELISA, FACS, SPR/BLI, or similar).
• Proven ability to troubleshoot and optimize assays and experimental workflows.
• Strong organizational, data analysis, and presentation skills.
• Experience working with or coordinating external research partners (e.g., CROs) preferred.
• Self-motivated, adaptable, and able to thrive in a fast-paced, collaborative startup environment.