Demo

Laboratory Manager

Case Western Reserve University School of Medicine
Cleveland, OH Full Time
POSTED ON 4/28/2025
AVAILABLE BEFORE 5/28/2025

The Gryder lab is :

  • pioneering new anti-cancer therapeutics, especially drugs targeting transcription factors and chromatin regulatory machinery
  • uncovering new mechanisms at work in gene control, using the integration of 3D genomics, epigenomics, transcriptomics, systems biology, and super-resolution imaging of nuclear condensate dynamics
  • mapping the core regulatory circuitry of human disease

We are seeking an experienced molecular biologist to lead the wet-lab operations of the Gryder Laboratory. We will work heavily with molecular biology (CRISPR, cloning, protein tagging, western blotting, cell culture), NGS library preparation (ChIP-seq, RNA-seq, HiC, CUTandTag, CUTandRUN), and microscopy (DNA and RNA FISH, immunofluorescence with super-resolution to identify nuclear condensates).

At the foundation of our lab, we are looking for a scientist who works with diligence, is well organized, pays great attention to detail and keeps the lab running smoothly. This will include performing wetlab experiments, troubleshooting new wet-lab technology development, teaching trainees / volunteers, developing systems of semi-automation with streamlined workflows (including the evaluation / purchase of new equipment), and keeping detailed records / inventory of biomaterials / experiments generated in the lab.

Intellectual exploration and discovery of epigenetic mechanisms is at the heart of this work.

We prioritize candidates who exhibit kindness, creativity, enthusiasm, and courage.

Find out more at

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