Research Scientist

Research Scientist, In Vitro Pharmacology (Histology Focus)

Department: In Vitro Pharmacology

Reports To: VP, In Vitro Pharmacology

Position Summary

We are seeking a Research Scientist with strong expertise in histology and histopathology to support in vitro and translational research activities.

This role will be responsible for tissue processing, histological analysis, and staining (with a strong emphasis on IHC), while also contributing to broader vitro studies. The ideal candidate is hands-on, detail-oriented, and experienced in preparing and analyzing tissue samples in a regulated laboratory environment.

You will work closely with both In Vivo and In Vitro teams, ensuring high-quality sample processing, accurate data generation, and compliance with GLP and EHS standards.

Key Responsibilities

Histology and Tissue Processing (Core Focus)

• Perform tissue processing and embedding (FFPE) for a variety of study types
• Conduct microtome sectioning and cryostat sectioning
• Execute histological staining, including: o Immunohistochemistry (IHC) primary focus
• H&E staining oSpecial stains (e.g., Sirius Red and others as needed)
• Ensure proper handling, labeling, and tracking of tissue samples
• Maintain highquality histological output for downstream analysis
  
  

Research Execution and Study Support

• Support the design, planning, and execution of in vitro and translational studies
• Collaborate with In Vivo team on sample receipt, processing, and integration into downstream assays
• Apply additional laboratory techniques as needed (e.g., ELISA, cellbased assays, molecular techniques)
• Troubleshoot experimental workflows and optimize histologyrelated processes
  
  

Data Analysis and Documentation

• Review and interpret histology data and staining results
• Maintain accurate and wellorganized laboratory records in compliance with GLP and internal SOPs
• Contribute to study reports, data summaries, and scientific documentation
• Assist in development and revision of SOPs for histology and related workflows
  
  

Lab Operations and Quality

• Ensure compliance with GLP, nonGLP, and EHS standards
• Maintain histology lab equipment (microtome, cryostat, staining systems, etc.)
• Support lab organization, workflow efficiency, and inventory management
• Participate in audits, inspections, and quality processes as needed
  
  

Training and Collaboration

• Train and mentor junior staff in histology techniques and best practices
• Serve as a technical resource for histologyrelated activities across teams
• Collaborate crossfunctionally with In Vivo, QA, and other departments
  
  

Qualifications

Required

• Bachelor’s or Master’s degree in Biology, Pathology, or related field
• 36 years of handson histology experience in a research or CRO environment
• Strong handson experience with: o IHC staining (critical requirement)
• FFPE tissue processing and embedding oMicrotome sectioning and cryostat operation
• H&E and special stains
• Experience working with animal tissues and preclinical samples
• Familiarity with GLP or regulated laboratory environments
• Strong attention to detail and documentation practices
  
  

Preferred

• Experience supporting preclinical or translational studies
• Familiarity with digital pathology or image analysis tools
• Experience with additional in vitro techniques (ELISA, PCR, etc.)
• AALAS certification or relevant histology certifications
  
  

What We’re Looking For

• A histology specialist first, scientist second
• Handson and detailoriented with strong technical execution
• Able to manage sample workflows efficiently and independently
• Collaborative and comfortable working across teams
• Strong focus on quality, consistency, and reproducibility
  
  

Why Join Us

• Work on diverse preclinical and translational research programs
• Highimpact role supporting both in vivo and in vitro studies
• Collaborative, sciencedriven team environment
• Opportunity to expand technical expertise across multiple platforms