Demo

Research Associate I/II, Production

BigHat Biosciences
San Mateo, CA Full Time
POSTED ON 5/21/2026
AVAILABLE BEFORE 6/19/2026
Department: Lab Science

Location: San Mateo, CA

Description

The Role: BigHat Biosciences is seeking a self-motivated individual for a Research Associate I/II, Production, role to power our high-throughput, automated platform for antibody production and deep molecular characterization.

Key Responsibilities

  • Perform automated and manual high-throughput processing on the BigHat platform, including DNA preparation, protein expression, and protein characterization.
  • Contribute to the scaling up of BigHat’s platform and production-grade data generation.
  • Support BigHat’s Platform Reagents & Assay Support (PRAS) function by contributing to in-house reagent manufacturing efforts.
  • Execute experiments to optimize the performance efficiency of BigHat’s platform.
  • Keep a detailed record of all experiments using BigHat’s documentation tools, and clearly communicate results and challenges.
  • Collaborate on the creation of laboratory standard operating procedures (SOPs) for sample processing.
  • Collaborate closely with BigHat team members to identify, design, and implement critical process and operational improvements to production workflows and laboratory systems.
  • Operate automated liquid handlers and analytical instruments to ensure all lab and platform operations run efficiently.

Skills Knowledge And Expertise

  • BS in Biology or Chemistry, with 1 year(s) of industry experience
  • Experience in process execution, laboratory method development, optimization, and troubleshooting.
  • Hands-on experience with, or interest in, automated liquid handlers (e.g. Hamilton, OpenTrons, Tecan, Agilent systems). Experience with LIMS is a nice-to-have.
  • Experience with molecular biology techniques and general lab practices.
  • Efficient time management and ability to work on several projects simultaneously, in a dynamic start-up environment.
  • Strong interpersonal skills and ability to effectively communicate with members of a multidisciplinary team.
  • Excellent record keeping abilities to document experimental work and analytical data.
  • Nice-to-haves include previous experience working with barcoding systems, inventory tracking, and experience with Google Workspace tools (Docs, Sheets, Slides, etc.)

Total Rewards

The salary estimated for this position is $75,000 - $105,000 bonus options benefits. Compensation will vary depending on job-related knowledge, skills, and experience. Actual compensation will be confirmed in writing at the time of the offer.

What BigHat Offers

  • Range of health insurance plan options through Anthem and Kaiser (monthly credit if benefit waived)
  • Dental, and vision coverage through Guardian
  • Additional well-being benefits through Nayya, OneMedical, Wagmo, Rula, and more
  • 401(k) with company match
  • DTO, two weeks of company-wide shutdown, and 12 company holidays
  • Paid parental leave

Salary.com Estimation for Research Associate I/II, Production in San Mateo, CA
$98,042 to $120,634
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